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CPLX4 and CTSA
Data Source:
BioGRID
(two hybrid)
CPLX4
CTSA
Description
complexin 4
cathepsin A
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
SNARE Complex
Terminal Bouton
Extracellular Region
Lysosome
Endoplasmic Reticulum
Membrane
Azurophil Granule Lumen
Lysosomal Lumen
Intracellular Membrane-bounded Organelle
Extracellular Exosome
Lumenal Side Of Lysosomal Membrane
Molecular Function
SNARE Binding
Protein Binding
Syntaxin Binding
Carboxypeptidase Activity
Serine-type Carboxypeptidase Activity
Enzyme Activator Activity
Biological Process
Visual Perception
Synaptic Vesicle Exocytosis
Regulation Of Neurotransmitter Secretion
Response To Stimulus
Proteolysis
Glycosphingolipid Metabolic Process
Intracellular Protein Transport
Regulation Of Protein Stability
Neutrophil Degranulation
Regulation Of Catalytic Activity
Regulation Of Chaperone-mediated Autophagy
Negative Regulation Of Chaperone-mediated Autophagy
Pathways
Glycosphingolipid metabolism
MHC class II antigen presentation
Sialic acid metabolism
Defective NEU1 causes sialidosis
Neutrophil degranulation
Drugs
Diseases
Galactosialidosis
GWAS
Cardiac troponin-I levels (
31014085
)
Chronotype (
27494321
)
Macular thickness (
30535121
)
Morning vs. evening chronotype (
27494321
)
Interacting Genes
92 interacting genes:
ADIPOQ
AGTRAP
AIG1
AOC3
APOD
AQP1
AQP9
ASGR1
ATP6V0C
BNIP2
C14orf180
C1GALT1
C3orf52
C5
CACNG1
CCL4L2
CD81
CDIPT
CDS2
CLDND2
CLEC4G
CLN6
CMTM5
CNIH1
CTSA
CTXN3
CYB5B
CYBC1
CYP4F2
DEFB127
EMD
GAD2
GIMAP1
GRM2
HACD1
HHATL
HMOX1
INSIG2
LPAR3
MAL
MALL
MAN2B2
MGAM
NINJ2
NRM
ORMDL1
PGAP2
PLN
PLP2
PLPP4
PNLIPRP1
PTPN9
RTP2
SEC22B
SELENOK
SFTPC
SLC30A2
SLC30A8
SLC35A1
SLC35A4
SLC35B4
SLC38A7
SLC39A9
SMCO4
STX3
STX8
SYNJ2BP
TF
TMEM120B
TMEM14A
TMEM14B
TMEM19
TMEM201
TMEM203
TMEM218
TMEM229B
TMEM243
TMEM254
TMEM267
TMEM60
TMEM79
TMEM86A
TMEM97
TRAF3IP3
TSPO2
UBIAD1
VAMP4
VAMP5
VKORC1
WFDC2
YIPF6
ZFPL1
45 interacting genes:
AHNAK2
AQP2
AQP6
ARL13B
ASPH
BSND
CD79A
COQ9
CPLX4
CREB3L1
CSPG5
ERGIC3
FAM209A
FKBP7
FNDC9
GLB1
GORAB
HIBADH
LAMP2
LMNA
LTB4R2
MFSD14B
MGST3
MUC1
MYG1
NEU1
PSCA
REEP4
RHBDD1
RNF122
SAR1A
SGMS2
SIGLEC12
SLC18A1
SLC30A2
SPN
SSMEM1
STX2
THAP4
TMEM139
TMEM154
TMEM237
TMEM31
TMEM35A
TMX2
Entrez ID
339302
5476
HPRD ID
13091
02020
Ensembl ID
ENSG00000166569
ENSG00000064601
Uniprot IDs
Q7Z7G2
B4E324
P10619
X6R5C5
X6R8A1
PDB IDs
1IVY
3BP4
3BP7
3BXN
4AZ0
4AZ3
4CI9
4CIA
4CIB
4MWS
4MWT
6WIA
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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