CPLX4 and AOC3

Data Source:
BioGRID (two hybrid)

		CPLX4	AOC3
Description		complexin 4	amine oxidase copper containing 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane SNARE Complex Terminal Bouton	Cytoplasm Early Endosome Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Microvillus Cell Surface Integral Component Of Membrane
	Molecular Function	SNARE Binding Protein Binding Syntaxin Binding	Copper Ion Binding Calcium Ion Binding Protein Binding Primary Amine Oxidase Activity Identical Protein Binding Protein Heterodimerization Activity Quinone Binding Tryptamine:oxygen Oxidoreductase (deaminating) Activity Aminoacetone:oxygen Oxidoreductase(deaminating) Activity Aliphatic-amine Oxidase Activity Phenethylamine:oxygen Oxidoreductase (deaminating) Activity
	Biological Process	Visual Perception Synaptic Vesicle Exocytosis Regulation Of Neurotransmitter Secretion Response To Stimulus	Xenobiotic Metabolic Process Inflammatory Response Cell Adhesion Amine Metabolic Process Response To Antibiotic Negative Regulation Of Primary Amine Oxidase Activity
Pathways			Phase I - Functionalization of compounds
Drugs			Phenelzine Hydralazine 6-hydroxydopa quinone
Diseases
GWAS		Cardiac troponin-I levels ( 31014085) Chronotype ( 27494321) Macular thickness ( 30535121) Morning vs. evening chronotype ( 27494321)
Interacting Genes		92 interacting genes: ADIPOQ AGTRAP AIG1 AOC3 APOD AQP1 AQP9 ASGR1 ATP6V0C BNIP2 C14orf180 C1GALT1 C3orf52 C5 CACNG1 CCL4L2 CD81 CDIPT CDS2 CLDND2 CLEC4G CLN6 CMTM5 CNIH1 CTSA CTXN3 CYB5B CYBC1 CYP4F2 DEFB127 EMD GAD2 GIMAP1 GRM2 HACD1 HHATL HMOX1 INSIG2 LPAR3 MAL MALL MAN2B2 MGAM NINJ2 NRM ORMDL1 PGAP2 PLN PLP2 PLPP4 PNLIPRP1 PTPN9 RTP2 SEC22B SELENOK SFTPC SLC30A2 SLC30A8 SLC35A1 SLC35A4 SLC35B4 SLC38A7 SLC39A9 SMCO4 STX3 STX8 SYNJ2BP TF TMEM120B TMEM14A TMEM14B TMEM19 TMEM201 TMEM203 TMEM218 TMEM229B TMEM243 TMEM254 TMEM267 TMEM60 TMEM79 TMEM86A TMEM97 TRAF3IP3 TSPO2 UBIAD1 VAMP4 VAMP5 VKORC1 WFDC2 YIPF6 ZFPL1	13 interacting genes: ARL13B CLDN9 CPLX4 CREB3L1 DARS2 FNDC9 HSD17B13 LMNA MYBPC2 PRRG4 SGTA STX1A VAV1
Entrez ID		339302	8639
HPRD ID		13091	04770
Ensembl ID		ENSG00000166569	ENSG00000131471
Uniprot IDs		Q7Z7G2	Q16853 Q9UEU7
PDB IDs			1PU4 1US1 2C10 2C11 2Y73 2Y74 3ALA 4BTW 4BTX 4BTY
Enriched GO Terms of Interacting Partners?
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