PGAP2 and CISD2

Data Source:
BioGRID (two hybrid)

		PGAP2	CISD2
Description		post-GPI attachment to proteins 2	CDGSH iron sulfur domain 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Integral Component Of Membrane	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Protein-containing Complex Perinuclear Endoplasmic Reticulum
	Molecular Function	Protein Binding	RNA Binding Protein Binding Protein Homodimerization Activity Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding
	Biological Process	GPI Anchor Biosynthetic Process	Autophagy Of Mitochondrion Multicellular Organism Aging Regulation Of Autophagy
Pathways
Drugs
Diseases			Wolfram syndrome (WFS); DIDMOAD syndrome
GWAS		Malaria ( 31844061)	Asthma and attention deficit hyperactivity disorder ( 31619474) Estimated glomerular filtration rate ( 31152163) Primary biliary cholangitis ( 26394269) Schizophrenia ( 28991256) Type 2 diabetes ( 28869590)
Interacting Genes		31 interacting genes: AMIGO1 ARL13B BIK CD79A CGRRF1 CISD2 CLDN7 CLSTN3 COMT CPLX4 CREB3L1 CYSRT1 ERGIC3 F11R FAM209A FNDC9 GJA5 GJA8 GJB5 GPR152 GPX8 KASH5 KRTAP10-3 KRTAP10-9 LRRC4C PDZK1IP1 SSMEM1 STX1A TMEM52B TMEM9 TMPRSS2	58 interacting genes: AIG1 APOL2 APP AQP10 BCL2L2 BET1 BMP10 BTN2A2 C14orf180 C2CD2L C4orf3 CDIPT CFHR5 CLDN10 CLN6 CYBC1 EHHADH EMD FAM241B GALNT15 GAST GPR37L1 HHATL IER3 KIR2DL3 LEPROTL1 LRP10 MAN2B2 MIP NAPB NRG4 NSG1 PGAP2 PLPP4 PLPPR2 PNKP POMGNT1 RTP2 RUSF1 SEC22A SERP2 SLC13A3 SLC35B4 SMIM1 SNORC SPP1 STX12 STX7 THSD7B TMEM187 TMEM243 TMEM43 TMEM86A TSPAN33 TTPA VAMP4 VKORC1L1 YIPF6
Entrez ID		27315	493856
HPRD ID		17016	17413
Ensembl ID		ENSG00000148985	ENSG00000145354
Uniprot IDs		A0A024RCC6 A0A024RCD5 A0A0A0MS75 A0A0S2Z568 A8MYS5 B7Z2X5 H0YDQ4 Q9UHJ9	Q8N5K1
PDB IDs			3FNV 4OO7 4OOA
Enriched GO Terms of Interacting Partners?
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