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BBC3 and MYPOP
Data Source:
BioGRID
(two hybrid)
BBC3
MYPOP
Description
BCL2 binding component 3
Myb related transcription factor, partner of profilin
Image
No pdb structure
GO Annotations
Cellular Component
Mitochondrion
Lysosome
Nucleus
Molecular Function
Protein Binding
ATPase Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
Protein Binding
Identical Protein Binding
Biological Process
Release Of Cytochrome C From Mitochondria
Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Positive Regulation Of Release Of Cytochrome C From Mitochondria
Execution Phase Of Apoptosis
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
Pathways
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members
Activation of PUMA and translocation to mitochondria
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
FOXO-mediated transcription of cell death genes
Drugs
Diseases
GWAS
Monocyte count (
27863252
)
White blood cell count (
32888494
)
Asthma (
31959851
)
Interacting Genes
14 interacting genes:
BAX
BCL2
BCL2A1
BCL2L1
BCL2L2
FHL5
HGS
HSD17B13
MCL1
MYPOP
NDUFAB1
UBASH3B
WDR5
ZNF438
42 interacting genes:
AKAP8L
BAG4
BBC3
CARD10
CHIC2
CIB4
CYSRT1
FHL3
HNRNPH1
HNRNPK
HOXA1
KHDRBS3
KIFAP3
KRT40
KRTAP1-3
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP12-2
KRTAP19-5
KRTAP19-6
KRTAP3-1
KRTAP5-6
MDFI
MTUS2
NBPF19
NCK2
NECAB2
NOTCH2NLA
PFN1
PFN2
PRDM14
PRR3
RBM3
RBMX
RBMY1A1
RBPMS2
SAT1
SYNCRIP
TGM1
TNS2
TRA2B
Entrez ID
27113
339344
HPRD ID
16165
17352
Ensembl ID
ENSG00000105327
ENSG00000176182
Uniprot IDs
Q96PG8
Q9BXH1
Q86VE0
PDB IDs
2M04
4BPI
4BPJ
4BPK
4HNJ
5UUL
6QFM
6QG8
6TQP
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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