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BBC3 and NDUFAB1
Data Source:
BioGRID
(two hybrid)
BBC3
NDUFAB1
Description
BCL2 binding component 3
NADH:ubiquinone oxidoreductase subunit AB1
Image
GO Annotations
Cellular Component
Mitochondrion
Lysosome
Nucleoplasm
Mitochondrion
Mitochondrial Inner Membrane
Mitochondrial Respiratory Chain Complex I
Mitochondrial Matrix
Mitochondrial Large Ribosomal Subunit
Mitochondrial Membrane
Molecular Function
Protein Binding
ATPase Binding
Acyl Binding
Acyl Carrier Activity
Fatty Acid Binding
Calcium Ion Binding
Protein Binding
NADH Dehydrogenase (ubiquinone) Activity
Biological Process
Release Of Cytochrome C From Mitochondria
Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Positive Regulation Of Release Of Cytochrome C From Mitochondria
Execution Phase Of Apoptosis
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Mitochondrial Electron Transport, NADH To Ubiquinone
Fatty Acid Biosynthetic Process
Protein Lipoylation
Mitochondrial Respiratory Chain Complex I Assembly
Pathways
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members
Activation of PUMA and translocation to mitochondria
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
FOXO-mediated transcription of cell death genes
Glyoxylate metabolism and glycine degradation
Respiratory electron transport
Complex I biogenesis
Mitochondrial Fatty Acid Beta-Oxidation
Drugs
NADH
Diseases
GWAS
Monocyte count (
27863252
)
White blood cell count (
32888494
)
Bipolar disorder (
17554300
)
Interacting Genes
14 interacting genes:
BAX
BCL2
BCL2A1
BCL2L1
BCL2L2
FHL5
HGS
HSD17B13
MCL1
MYPOP
NDUFAB1
UBASH3B
WDR5
ZNF438
35 interacting genes:
ACTN3
BBC3
BEX5
CCDC24
CNTF
EIF3B
ERBB3
FEM1A
FHL3
FNDC3B
HINFP
KCTD9
LMO2
LNX1
MBLAC1
MORN3
MRPL23
NOXA1
NRF1
NT5C3A
NTAQ1
OIP5
POP5
PPP1R16A
PSMC3
RBM18
SLIRP
SMYD3
THAP1
TLX3
TOX2
VAC14
ZNF19
ZNF410
ZNF829
Entrez ID
27113
4706
HPRD ID
16165
11951
Ensembl ID
ENSG00000105327
ENSG00000004779
Uniprot IDs
Q96PG8
Q9BXH1
O14561
PDB IDs
2M04
4BPI
4BPJ
4BPK
4HNJ
5UUL
6QFM
6QG8
6TQP
2DNW
5OOL
5OOM
5XTB
5XTC
5XTD
5XTH
5XTI
6ODD
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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