STX1B and SNAP23

Data Source:
BioGRID (pull down)

		STX1B	SNAP23
Description		syntaxin 1B	synaptosome associated protein 23
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Microtubule Organizing Center Spindle Cytosol Plasma Membrane Synaptic Vesicle Endomembrane System Membrane Integral Component Of Membrane Axon SNARE Complex Neuromuscular Junction Presynaptic Active Zone Membrane	Nucleoplasm Cytoplasm Mitochondrion Plasma Membrane Adherens Junction Focal Adhesion Phagocytic Vesicle Membrane SNARE Complex Specific Granule Membrane Specific Granule Azurophil Granule Neuron Projection Extracellular Exosome Tertiary Granule Membrane Presynapse
	Molecular Function	SNARE Binding Signaling Receptor Binding SNAP Receptor Activity Protein Binding Protein Kinase Binding Protein Domain Specific Binding	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Positive Regulation Of Neurotransmitter Secretion Intracellular Protein Transport Exocytosis Vesicle Docking Involved In Exocytosis Vesicle Fusion Regulation Of Gene Expression Regulation Of Synaptic Vesicle Priming Negative Regulation Of Neuron Projection Development Synaptic Vesicle Docking Regulation Of Exocytosis Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Docking Calcium Ion-regulated Exocytosis Of Neurotransmitter Regulation Of Synaptic Activity Spontaneous Neurotransmitter Secretion Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane Negative Regulation Of Synaptic Vesicle Recycling Positive Regulation Of Spontaneous Neurotransmitter Secretion Negative Regulation Of Macropinocytosis Positive Regulation Of Excitatory Postsynaptic Potential	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Histamine Secretion By Mast Cell Exocytosis Post-Golgi Vesicle-mediated Transport Vesicle Targeting Vesicle Fusion Protein Transport Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Neutrophil Degranulation Membrane Fusion
Pathways		Toxicity of botulinum toxin type C (botC) LGI-ADAM interactions	ER-Phagosome pathway Translocation of SLC2A4 (GLUT4) to the plasma membrane trans-Golgi Network Vesicle Budding Neutrophil degranulation
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body mass index ( 31453325) Body mass index variance ( 31453325) Dementia with Lewy bodies ( 29263008) Hip circumference ( 31453325) Hip circumference variance ( 31453325) Juvenile myoclonic epilepsy ( 30531953) Low density lipoprotein cholesterol levels ( 32154731) Parkinson's disease ( 25064009 32201043) Psoriasis ( 25574825) Response to metformin (IC50) ( 28173075) Waist circumference ( 31453325) Waist circumference variance ( 31453325)	Bipolar disorder ( 31043756)
Interacting Genes		29 interacting genes: ABHD16A ACBD5 AQP6 BET1 EBP ERGIC3 FAM161B FAM209A FAM81A FBXO28 FGA GJA8 GPR152 KCNN4 MMGT1 NAPB SNAP23 SNAP29 SNAP47 STX2 STX4 STXBP1 TMEM167B TXLNA UBE2I UNC13B VAMP1 VAMP2 VAMP5	32 interacting genes: ABI2 ABI3 CFTR FXR2 ITSN1 KIF5B MATR3 NAPA NAPB PRKCA SCAMP1 SCAMP2 SCGN SNAPIN SNTG1 STX11 STX12 STX1A STX1B STX3 STX4 STX5 STX6 STXBP2 STXBP5 TLK1 VAMP1 VAMP2 VAMP3 VAMP7 VAMP8 WASH2P
Entrez ID		112755	8773
HPRD ID		18126	03962
Ensembl ID		ENSG00000099365	ENSG00000092531
Uniprot IDs		P61266	A0A024R9R8 A8K287 O00161
PDB IDs			1NHL 3ZUS
Enriched GO Terms of Interacting Partners?
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