STX1B and FBXO28

Data Source:
BioGRID (two hybrid)

		STX1B	FBXO28
Description		syntaxin 1B	F-box protein 28
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Microtubule Organizing Center Spindle Cytosol Plasma Membrane Synaptic Vesicle Endomembrane System Membrane Integral Component Of Membrane Axon SNARE Complex Neuromuscular Junction Presynaptic Active Zone Membrane	Kinetochore Condensed Chromosome Kinetochore
	Molecular Function	SNARE Binding Signaling Receptor Binding SNAP Receptor Activity Protein Binding Protein Kinase Binding Protein Domain Specific Binding	Protein Binding Identical Protein Binding
	Biological Process	Positive Regulation Of Neurotransmitter Secretion Intracellular Protein Transport Exocytosis Vesicle Docking Involved In Exocytosis Vesicle Fusion Regulation Of Gene Expression Regulation Of Synaptic Vesicle Priming Negative Regulation Of Neuron Projection Development Synaptic Vesicle Docking Regulation Of Exocytosis Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Docking Calcium Ion-regulated Exocytosis Of Neurotransmitter Regulation Of Synaptic Activity Spontaneous Neurotransmitter Secretion Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane Negative Regulation Of Synaptic Vesicle Recycling Positive Regulation Of Spontaneous Neurotransmitter Secretion Negative Regulation Of Macropinocytosis Positive Regulation Of Excitatory Postsynaptic Potential	Protein Polyubiquitination
Pathways		Toxicity of botulinum toxin type C (botC) LGI-ADAM interactions
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body mass index ( 31453325) Body mass index variance ( 31453325) Dementia with Lewy bodies ( 29263008) Hip circumference ( 31453325) Hip circumference variance ( 31453325) Juvenile myoclonic epilepsy ( 30531953) Low density lipoprotein cholesterol levels ( 32154731) Parkinson's disease ( 25064009 32201043) Psoriasis ( 25574825) Response to metformin (IC50) ( 28173075) Waist circumference ( 31453325) Waist circumference variance ( 31453325)
Interacting Genes		29 interacting genes: ABHD16A ACBD5 AQP6 BET1 EBP ERGIC3 FAM161B FAM209A FAM81A FBXO28 FGA GJA8 GPR152 KCNN4 MMGT1 NAPB SNAP23 SNAP29 SNAP47 STX2 STX4 STXBP1 TMEM167B TXLNA UBE2I UNC13B VAMP1 VAMP2 VAMP5	22 interacting genes: AGGF1 CAVIN1 CSNK2A1 CTNNA3 EMILIN1 EMILIN3 EXOC7 GCC1 GK GOLGA2 GOLGA6L9 HOMER3 PLEKHF2 PMF1 PSMC3 SDCBP2 SKP1 SPAG5 STX1B TOP2A TRAF2 TRAF5
Entrez ID		112755	23219
HPRD ID		18126	12367
Ensembl ID		ENSG00000099365	ENSG00000143756
Uniprot IDs		P61266	Q9NVF7
PDB IDs
Enriched GO Terms of Interacting Partners?
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