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GJA5 and NKG7
Data Source:
BioGRID
(two hybrid)
GJA5
NKG7
Description
gap junction protein alpha 5
natural killer cell granule protein 7
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Integral Component Of Plasma Membrane
Gap Junction
Connexin Complex
Intercalated Disc
Cell Projection
Plasma Membrane
Integral Component Of Plasma Membrane
Molecular Function
Gap Junction Channel Activity
Protein Binding
Gap Junction Hemi-channel Activity
Connexin Binding
Gap Junction Channel Activity Involved In SA Node Cell-atrial Cardiac Muscle Cell Electrical Coupling
Gap Junction Channel Activity Involved In Cardiac Conduction Electrical Coupling
Gap Junction Channel Activity Involved In Atrial Cardiac Muscle Cell-AV Node Cell Electrical Coupling
Gap Junction Channel Activity Involved In AV Node Cell-bundle Of His Cell Electrical Coupling
Gap Junction Channel Activity Involved In Bundle Of His Cell-Purkinje Myocyte Electrical Coupling
Gap Junction Channel Activity Involved In Purkinje Myocyte-ventricular Cardiac Muscle Cell Electrical Coupling
Disordered Domain Specific Binding
Protein Binding
Biological Process
Angiogenesis
Negative Regulation Of Glomerular Filtration
Outflow Tract Morphogenesis
Endothelium Development
Mitral Valve Development
Pulmonary Valve Formation
Ventricular Septum Development
Atrial Septum Development
Potassium Ion Transport
Cell-cell Signaling
Cell Communication By Chemical Coupling
Regulation Of Cell Communication By Electrical Coupling
Positive Regulation Of Cell Communication By Chemical Coupling
Gap Junction Assembly
Negative Regulation Of Blood Pressure
Positive Regulation Of Vasoconstriction
Artery Morphogenesis
Transmembrane Transport
Regulation Of Cardiac Muscle Contraction
Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization
SA Node Cell To Atrial Cardiac Muscle Cell Communication By Electrical Coupling
Atrial Cardiac Muscle Cell To AV Node Cell Communication By Electrical Coupling
AV Node Cell To Bundle Of His Cell Communication By Electrical Coupling
Bundle Of His Cell To Purkinje Myocyte Communication By Electrical Coupling
Purkinje Myocyte To Ventricular Cardiac Muscle Cell Communication By Electrical Coupling
Cell Communication By Electrical Coupling Involved In Cardiac Conduction
Regulation Of AV Node Cell Action Potential
Regulation Of Bundle Of His Cell Action Potential
Regulation Of Purkinje Myocyte Action Potential
Regulation Of Atrial Cardiac Muscle Cell Action Potential
Vasomotion
Pathways
Gap junction assembly
Drugs
Diseases
Atrial fibrillation
GWAS
Atrial fibrillation (
30061737
29892015
)
Cognitive performance (
20125193
)
Methotrexate-induced interstitial lung disease in rheumatoid arthritis (
28500057
)
PR interval (
32439900
)
Neutrophil count (
32888494
27863252
)
Neutrophil percentage of white cells (
32888494
)
Interacting Genes
34 interacting genes:
AAR2
ABHD16A
BLCAP
C4orf3
EMP3
FCER1G
GJA1
GJB2
IGFBP5
LEPROT
LEPROTL1
LHFPL2
MARK1
MFSD5
MS4A13
NIPAL3
NKG7
PGAP2
PRAF2
PRKACA
RIMS3
RPRM
SLC13A4
SLC30A2
SLC35F1
SLC41A1
SLC41A2
SLC66A1
TMBIM6
TMEM107
TREX1
UBQLN4
VRK2
YIPF6
45 interacting genes:
AGTRAP
AMIGO1
AQP6
ARL13B
ATP6AP2
BAMBI
CD53
CD79A
CLDN7
CLEC2D
CLEC4E
CLSTN3
CREB3
EBP
EDA2R
ERGIC3
FAM210B
FFAR2
FNDC9
GJA5
GORAB
GPX8
ISLR2
KLRC1
LHFPL5
LMNA
MFSD6
MGST3
MS4A3
MSR1
MUC1
OPRK1
PEX12
RAMP1
RNF24
SLC18A2
SLC30A8
STOM
STX1A
TLCD4
TMEM106C
TMEM130
TMEM139
TMEM80
TMEM88
Entrez ID
2702
4818
HPRD ID
08699
16188
Ensembl ID
ENSG00000265107
ENSG00000105374
Uniprot IDs
P36382
X5D2H9
Q16617
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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