NKG7 and CLEC2D

Data Source:
BioGRID (two hybrid)

		NKG7	CLEC2D
Description		natural killer cell granule protein 7	C-type lectin domain family 2 member D
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane
	Molecular Function	Protein Binding	Transmembrane Signaling Receptor Activity Carbohydrate Binding Natural Killer Cell Lectin-like Receptor Binding
	Biological Process		Cell Surface Receptor Signaling Pathway Regulation Of Immune Response
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Neutrophil count ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494)	Autoimmune thyroid disease ( 32581359) HDL cholesterol levels x short total sleep time interaction (1df test) ( 31719535) HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Multiple sclerosis ( 31604244)
Interacting Genes		45 interacting genes: AGTRAP AMIGO1 AQP6 ARL13B ATP6AP2 BAMBI CD53 CD79A CLDN7 CLEC2D CLEC4E CLSTN3 CREB3 EBP EDA2R ERGIC3 FAM210B FFAR2 FNDC9 GJA5 GORAB GPX8 ISLR2 KLRC1 LHFPL5 LMNA MFSD6 MGST3 MS4A3 MSR1 MUC1 OPRK1 PEX12 RAMP1 RNF24 SLC18A2 SLC30A8 STOM STX1A TLCD4 TMEM106C TMEM130 TMEM139 TMEM80 TMEM88	33 interacting genes: - ADIPOQ ATP6V0C B3GALT5 BRICD5 CD68 CLDN19 CLDN2 CLEC2A CLRN2 CXCL9 DEFB121 ENTPD8 ERMP1 FAM3C FNDC9 GPR42 IL1RL1 KLRB1 KLRC1 LEPROTL1 NKG7 PLLP PLN PLP1 RPRM SEC22A SHMT2 SYT15 TM4SF18 TMEM190 TMEM80 TSPAN4
Entrez ID		4818	29121
HPRD ID		16188	16134
Ensembl ID		ENSG00000105374	ENSG00000069493
Uniprot IDs		Q16617	Q9UHP7 W8JXM2
PDB IDs			4QKG 4QKH 4QKI 4QKJ 4WCO 5MGT
Enriched GO Terms of Interacting Partners?
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