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GJA5 and PRAF2
Data Source:
BioGRID
(two hybrid)
GJA5
PRAF2
Description
gap junction protein alpha 5
PRA1 domain family member 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Integral Component Of Plasma Membrane
Gap Junction
Connexin Complex
Intercalated Disc
Cell Projection
Endosome Membrane
Membrane
Integral Component Of Membrane
Molecular Function
Gap Junction Channel Activity
Protein Binding
Gap Junction Hemi-channel Activity
Connexin Binding
Gap Junction Channel Activity Involved In SA Node Cell-atrial Cardiac Muscle Cell Electrical Coupling
Gap Junction Channel Activity Involved In Cardiac Conduction Electrical Coupling
Gap Junction Channel Activity Involved In Atrial Cardiac Muscle Cell-AV Node Cell Electrical Coupling
Gap Junction Channel Activity Involved In AV Node Cell-bundle Of His Cell Electrical Coupling
Gap Junction Channel Activity Involved In Bundle Of His Cell-Purkinje Myocyte Electrical Coupling
Gap Junction Channel Activity Involved In Purkinje Myocyte-ventricular Cardiac Muscle Cell Electrical Coupling
Disordered Domain Specific Binding
Protein Binding
Biological Process
Angiogenesis
Negative Regulation Of Glomerular Filtration
Outflow Tract Morphogenesis
Endothelium Development
Mitral Valve Development
Pulmonary Valve Formation
Ventricular Septum Development
Atrial Septum Development
Potassium Ion Transport
Cell-cell Signaling
Cell Communication By Chemical Coupling
Regulation Of Cell Communication By Electrical Coupling
Positive Regulation Of Cell Communication By Chemical Coupling
Gap Junction Assembly
Negative Regulation Of Blood Pressure
Positive Regulation Of Vasoconstriction
Artery Morphogenesis
Transmembrane Transport
Regulation Of Cardiac Muscle Contraction
Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization
SA Node Cell To Atrial Cardiac Muscle Cell Communication By Electrical Coupling
Atrial Cardiac Muscle Cell To AV Node Cell Communication By Electrical Coupling
AV Node Cell To Bundle Of His Cell Communication By Electrical Coupling
Bundle Of His Cell To Purkinje Myocyte Communication By Electrical Coupling
Purkinje Myocyte To Ventricular Cardiac Muscle Cell Communication By Electrical Coupling
Cell Communication By Electrical Coupling Involved In Cardiac Conduction
Regulation Of AV Node Cell Action Potential
Regulation Of Bundle Of His Cell Action Potential
Regulation Of Purkinje Myocyte Action Potential
Regulation Of Atrial Cardiac Muscle Cell Action Potential
Vasomotion
Protein Transport
L-glutamate Transmembrane Transport
Pathways
Gap junction assembly
Drugs
Diseases
Atrial fibrillation
GWAS
Atrial fibrillation (
30061737
29892015
)
Cognitive performance (
20125193
)
Methotrexate-induced interstitial lung disease in rheumatoid arthritis (
28500057
)
PR interval (
32439900
)
Interacting Genes
34 interacting genes:
AAR2
ABHD16A
BLCAP
C4orf3
EMP3
FCER1G
GJA1
GJB2
IGFBP5
LEPROT
LEPROTL1
LHFPL2
MARK1
MFSD5
MS4A13
NIPAL3
NKG7
PGAP2
PRAF2
PRKACA
RIMS3
RPRM
SLC13A4
SLC30A2
SLC35F1
SLC41A1
SLC41A2
SLC66A1
TMBIM6
TMEM107
TREX1
UBQLN4
VRK2
YIPF6
26 interacting genes:
ABHD16A
ADGRD1
AGR3
AQP6
ARL6IP5
CCR5
CD79A
CIAO2A
CLEC10A
EBAG9
GJA5
GJA8
GPR152
HIBADH
HSD17B11
MCEMP1
MIEF1
NDRG4
REEP4
RETREG3
RNF5
SLC10A6
TLCD4
TMEM14B
TMX2
ZDHHC15
Entrez ID
2702
11230
HPRD ID
08699
06596
Ensembl ID
ENSG00000265107
ENSG00000243279
Uniprot IDs
P36382
X5D2H9
A0A024QZ22
O60831
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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