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GJA5 and ABHD16A
Data Source:
BioGRID
(two hybrid)
GJA5
ABHD16A
Description
gap junction protein alpha 5
abhydrolase domain containing 16A, phospholipase
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Integral Component Of Plasma Membrane
Gap Junction
Connexin Complex
Intercalated Disc
Cell Projection
Membrane
Integral Component Of Membrane
Molecular Function
Gap Junction Channel Activity
Protein Binding
Gap Junction Hemi-channel Activity
Connexin Binding
Gap Junction Channel Activity Involved In SA Node Cell-atrial Cardiac Muscle Cell Electrical Coupling
Gap Junction Channel Activity Involved In Cardiac Conduction Electrical Coupling
Gap Junction Channel Activity Involved In Atrial Cardiac Muscle Cell-AV Node Cell Electrical Coupling
Gap Junction Channel Activity Involved In AV Node Cell-bundle Of His Cell Electrical Coupling
Gap Junction Channel Activity Involved In Bundle Of His Cell-Purkinje Myocyte Electrical Coupling
Gap Junction Channel Activity Involved In Purkinje Myocyte-ventricular Cardiac Muscle Cell Electrical Coupling
Disordered Domain Specific Binding
Phospholipase Activity
Lysophospholipase Activity
Protein Binding
Palmitoyl-(protein) Hydrolase Activity
Acylglycerol Lipase Activity
Biological Process
Angiogenesis
Negative Regulation Of Glomerular Filtration
Outflow Tract Morphogenesis
Endothelium Development
Mitral Valve Development
Pulmonary Valve Formation
Ventricular Septum Development
Atrial Septum Development
Potassium Ion Transport
Cell-cell Signaling
Cell Communication By Chemical Coupling
Regulation Of Cell Communication By Electrical Coupling
Positive Regulation Of Cell Communication By Chemical Coupling
Gap Junction Assembly
Negative Regulation Of Blood Pressure
Positive Regulation Of Vasoconstriction
Artery Morphogenesis
Transmembrane Transport
Regulation Of Cardiac Muscle Contraction
Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization
SA Node Cell To Atrial Cardiac Muscle Cell Communication By Electrical Coupling
Atrial Cardiac Muscle Cell To AV Node Cell Communication By Electrical Coupling
AV Node Cell To Bundle Of His Cell Communication By Electrical Coupling
Bundle Of His Cell To Purkinje Myocyte Communication By Electrical Coupling
Purkinje Myocyte To Ventricular Cardiac Muscle Cell Communication By Electrical Coupling
Cell Communication By Electrical Coupling Involved In Cardiac Conduction
Regulation Of AV Node Cell Action Potential
Regulation Of Bundle Of His Cell Action Potential
Regulation Of Purkinje Myocyte Action Potential
Regulation Of Atrial Cardiac Muscle Cell Action Potential
Vasomotion
Phosphatidylserine Catabolic Process
Protein Phosphopantetheinylation
Monoacylglycerol Catabolic Process
Macromolecule Depalmitoylation
Prostaglandin Catabolic Process
Pathways
Gap junction assembly
Drugs
Diseases
Atrial fibrillation
GWAS
Atrial fibrillation (
30061737
29892015
)
Cognitive performance (
20125193
)
Methotrexate-induced interstitial lung disease in rheumatoid arthritis (
28500057
)
PR interval (
32439900
)
Asthma (
31619474
)
Asthma (childhood onset) (
31619474
)
Asthma and major depressive disorder (
31619474
)
Autism spectrum disorder or schizophrenia (
28540026
)
Blood protein levels (
28240269
)
Inflammatory bowel disease (
28067908
)
Malaria (
31844061
)
Monocyte percentage of white cells (
32888494
)
Ulcerative colitis (
28067908
)
Interacting Genes
34 interacting genes:
AAR2
ABHD16A
BLCAP
C4orf3
EMP3
FCER1G
GJA1
GJB2
IGFBP5
LEPROT
LEPROTL1
LHFPL2
MARK1
MFSD5
MS4A13
NIPAL3
NKG7
PGAP2
PRAF2
PRKACA
RIMS3
RPRM
SLC13A4
SLC30A2
SLC35F1
SLC41A1
SLC41A2
SLC66A1
TMBIM6
TMEM107
TREX1
UBQLN4
VRK2
YIPF6
69 interacting genes:
AGPAT3
AQP6
AQP7
ATP5MC3
ATP5PF
BRI3
CBARP
CIDEB
CREB3
CYP1A2
DNAJC1
DTX2
EBP
ERGIC3
FDPS
FKBP7
GDAP1
GJA5
GOLT1A
GORAB
GPR152
GPRC5C
GYPC
HM13
HNRNPA1
HSD17B13
IFITM1
IFITM3
ITGAM
LTA
MLH1
MT-ND3
MT-ND4
PERP
PILRB
PKMYT1
POLE
PRAF2
PTGS2
RETREG3
RHBDD2
RHBDL1
RNF5
SAFB
SEC22B
SERF1A
SERF1B
SLC10A1
SLC30A2
SLC7A8
SPAG4
SPAG7
STMN4
STX1B
TM4SF19
TMEM139
TMEM143
TMEM147
TMEM14B
TMEM222
TMEM237
TMEM31
TMEM65
TSPAN2
UNC93A
UPF1
VAMP5
VMA21
WBP1L
Entrez ID
2702
7920
HPRD ID
08699
15929
Ensembl ID
ENSG00000265107
ENSG00000204427
Uniprot IDs
P36382
X5D2H9
A0A1U9X777
B3KNX9
O95870
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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