GJA4 and MS4A13

Data Source:
BioGRID (two hybrid)

		GJA4	MS4A13
Description		gap junction protein alpha 4	membrane spanning 4-domains A13
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Gap Junction Connexin Complex	Integral Component Of Membrane
	Molecular Function	Gap Junction Channel Activity Protein Binding	Protein Binding
	Biological Process	Blood Vessel Development Endothelium Development Calcium Ion Transport Cell-cell Junction Assembly Cell-cell Signaling Response To Pain Transmembrane Transport
Pathways		Gap junction assembly
Drugs
Diseases
GWAS		Formal thought disorder in schizophrenia ( 22648509) Triglyceride levels x thiazide or thiazide-like diuretics use interaction ( 31806883)	Congenital heart disease (maternal effect) ( 28468790) Major depressive disorder ( 29317602) Metabolite levels (X-11787) ( 23934736)
Interacting Genes		5 interacting genes: CD81 MS4A13 OPRM1 SLC29A2 TMEM86B	61 interacting genes: AQP2 AQP6 ASGR2 ATP6V0E1 BEST1 BIK CBARP CD79A CLDN7 CREB3L1 CREB3L3 DAGLA EBP EDA EREG ERGIC3 EVA1A FAM209A FAM210B FFAR2 GJA4 GJA5 GJA8 GJB1 GJB5 GJB6 GJC3 GPR152 HERPUD2 JSRP1 KCNMB4 KLRC1 LHFPL5 LRRC3B MMGT1 MS4A3 NPDC1 ODF4 POMK RAMP1 RHCG RNF185 SCN3B SLC12A7 SLC13A4 SLC16A2 SLC18A1 SLC30A2 SLC39A2 SLC7A1 SPAG4 SSMEM1 TBXA2R TLCD4 TM4SF18 TMC4 TMEM14B TMEM237 TMEM52B TMEM74 VSIR
Entrez ID		2701	503497
HPRD ID		08509	17604
Ensembl ID		ENSG00000187513	ENSG00000204979
Uniprot IDs		P35212	Q5J8X5
PDB IDs
Enriched GO Terms of Interacting Partners?
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