GJA4 and SLC29A2

Data Source:
BioGRID (two hybrid)

		GJA4	SLC29A2
Description		gap junction protein alpha 4	solute carrier family 29 member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Gap Junction Connexin Complex	Nucleolus Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Basolateral Plasma Membrane Nuclear Membrane Presynapse
	Molecular Function	Gap Junction Channel Activity Protein Binding	Neurotransmitter Transmembrane Transporter Activity Nucleoside Transmembrane Transporter Activity Purine Nucleoside Transmembrane Transporter Activity Uridine Transmembrane Transporter Activity
	Biological Process	Blood Vessel Development Endothelium Development Calcium Ion Transport Cell-cell Junction Assembly Cell-cell Signaling Response To Pain Transmembrane Transport	Neurotransmitter Uptake Neurotransmitter Transport Adenine Transport Guanine Transport Nucleoside Transport Purine Nucleoside Transmembrane Transport Uridine Transport Adenosine Transport Hypoxanthine Transport Thymine Transport Pyrimidine-containing Compound Transmembrane Transport Neurotransmitter Reuptake Transport Across Blood-brain Barrier Nucleoside Transmembrane Transport
Pathways		Gap junction assembly	Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
Drugs			Ethanol
Diseases
GWAS		Formal thought disorder in schizophrenia ( 22648509) Triglyceride levels x thiazide or thiazide-like diuretics use interaction ( 31806883)	Bipolar disorder ( 21926972) Serum uric acid levels ( 32514006)
Interacting Genes		5 interacting genes: CD81 MS4A13 OPRM1 SLC29A2 TMEM86B	19 interacting genes: ALOX5AP CERS3 CERS4 CREB3 ERGIC3 GJA4 GPR152 LAPTM4B PLPP5 SERINC2 SLC10A1 SLC10A6 TMEM237 TMEM242 TMEM33 TMEM86B TMX2 UBQLN1 UBQLN2
Entrez ID		2701	3177
HPRD ID		08509	03662
Ensembl ID		ENSG00000187513	ENSG00000174669
Uniprot IDs		P35212	G5E943 Q14542 Q96FB2
PDB IDs
Enriched GO Terms of Interacting Partners?
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