MS4A13 and SPAG4

Data Source:
BioGRID (two hybrid)

		MS4A13	SPAG4
Description		membrane spanning 4-domains A13	sperm associated antigen 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Nuclear Envelope Nuclear Inner Membrane Cytoplasm Cytoskeleton Integral Component Of Membrane Motile Cilium Meiotic Nuclear Membrane Microtubule Tethering Complex
	Molecular Function	Protein Binding	Structural Molecule Activity Protein Binding Protein-membrane Adaptor Activity
	Biological Process		Nuclear Envelope Organization Spermatogenesis Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Congenital heart disease (maternal effect) ( 28468790) Major depressive disorder ( 29317602) Metabolite levels (X-11787) ( 23934736)	Blood protein levels ( 28240269) Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		61 interacting genes: AQP2 AQP6 ASGR2 ATP6V0E1 BEST1 BIK CBARP CD79A CLDN7 CREB3L1 CREB3L3 DAGLA EBP EDA EREG ERGIC3 EVA1A FAM209A FAM210B FFAR2 GJA4 GJA5 GJA8 GJB1 GJB5 GJB6 GJC3 GPR152 HERPUD2 JSRP1 KCNMB4 KLRC1 LHFPL5 LRRC3B MMGT1 MS4A3 NPDC1 ODF4 POMK RAMP1 RHCG RNF185 SCN3B SLC12A7 SLC13A4 SLC16A2 SLC18A1 SLC30A2 SLC39A2 SLC7A1 SPAG4 SSMEM1 TBXA2R TLCD4 TM4SF18 TMC4 TMEM14B TMEM237 TMEM52B TMEM74 VSIR	24 interacting genes: ABHD16A ASGR1 BMP10 CSGALNACT1 ERMP1 GOSR2 IGFBP5 MS4A13 NRM ODF1 PAXIP1 PGA4 PLN PTPN9 RUSF1 SCAMP4 SCD SEC22A SUN5 TMEM187 TMEM60 TNMD TRARG1 TSPO2
Entrez ID		503497	6676
HPRD ID		17604	04330
Ensembl ID		ENSG00000204979	ENSG00000061656
Uniprot IDs		Q5J8X5	Q9NPE6
PDB IDs
Enriched GO Terms of Interacting Partners?
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