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MS4A13 and RAMP1
Data Source:
BioGRID
(two hybrid)
MS4A13
RAMP1
Description
membrane spanning 4-domains A13
receptor activity modifying protein 1
Image
No pdb structure
GO Annotations
Cellular Component
Integral Component Of Membrane
Extracellular Space
Plasma Membrane
Integral Component Of Plasma Membrane
Cell Surface
Receptor Complex
Amylin Receptor Complex 1
CGRP Receptor Complex
Molecular Function
Protein Binding
Calcitonin Gene-related Peptide Receptor Activity
Protein Binding
Coreceptor Activity
Amylin Receptor Activity
Calcitonin Gene-related Peptide Binding
Biological Process
Angiogenesis
Calcium Ion Transport
Intracellular Protein Transport
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Regulation Of G Protein-coupled Receptor Signaling Pathway
Protein Transport
Receptor Internalization
Positive Regulation Of Protein Binding
Cellular Response To Hormone Stimulus
Positive Regulation Of Protein Glycosylation
Protein Localization To Plasma Membrane
Amylin Receptor Signaling Pathway
Calcitonin Gene-related Peptide Receptor Signaling Pathway
Pathways
G alpha (s) signalling events
Calcitonin-like ligand receptors
ADORA2B mediated anti-inflammatory cytokines production
Drugs
Pramlintide
Diseases
GWAS
Congenital heart disease (maternal effect) (
28468790
)
Major depressive disorder (
29317602
)
Metabolite levels (X-11787) (
23934736
)
Obesity-related traits (
23251661
)
Resting metabolic rate (
28476931
)
Interacting Genes
61 interacting genes:
AQP2
AQP6
ASGR2
ATP6V0E1
BEST1
BIK
CBARP
CD79A
CLDN7
CREB3L1
CREB3L3
DAGLA
EBP
EDA
EREG
ERGIC3
EVA1A
FAM209A
FAM210B
FFAR2
GJA4
GJA5
GJA8
GJB1
GJB5
GJB6
GJC3
GPR152
HERPUD2
JSRP1
KCNMB4
KLRC1
LHFPL5
LRRC3B
MMGT1
MS4A3
NPDC1
ODF4
POMK
RAMP1
RHCG
RNF185
SCN3B
SLC12A7
SLC13A4
SLC16A2
SLC18A1
SLC30A2
SLC39A2
SLC7A1
SPAG4
SSMEM1
TBXA2R
TLCD4
TM4SF18
TMC4
TMEM14B
TMEM237
TMEM52B
TMEM74
VSIR
9 interacting genes:
CALCA
CALCR
CALCRL
IAPP
MAL
MS4A13
NKG7
SLC31A2
VIPR1
Entrez ID
503497
10267
HPRD ID
17604
05515
Ensembl ID
ENSG00000204979
ENSG00000132329
Uniprot IDs
Q5J8X5
E9PC20
O60894
PDB IDs
2YX8
3N7P
3N7R
3N7S
4RWG
5V6Y
6D1U
6E3Y
6UMG
6ZHO
6ZIS
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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