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MS4A13 and SCN3B
Data Source:
BioGRID
(two hybrid)
MS4A13
SCN3B
Description
membrane spanning 4-domains A13
sodium voltage-gated channel beta subunit 3
Image
No pdb structure
GO Annotations
Cellular Component
Integral Component Of Membrane
Voltage-gated Sodium Channel Complex
Plasma Membrane
Integral Component Of Membrane
Z Disc
Molecular Function
Protein Binding
Voltage-gated Ion Channel Activity
Protein Binding
Sodium Channel Regulator Activity
Sodium Channel Inhibitor Activity
Ion Channel Binding
Voltage-gated Sodium Channel Activity Involved In Cardiac Muscle Cell Action Potential
Biological Process
Sodium Ion Transport
Nervous System Development
Positive Regulation Of Heart Rate
Positive Regulation Of Sodium Ion Transport
Sensory Perception Of Pain
Sodium Ion Transmembrane Transport
Membrane Depolarization
Cardiac Muscle Contraction
Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization
Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization
Protein Localization To Plasma Membrane
Cardiac Muscle Cell Action Potential Involved In Contraction
Ventricular Cardiac Muscle Cell Action Potential
Membrane Depolarization During Action Potential
Membrane Depolarization During Cardiac Muscle Cell Action Potential
Atrial Cardiac Muscle Cell Action Potential
SA Node Cell Action Potential
Regulation Of Heart Rate By Cardiac Conduction
Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways
Interaction between L1 and Ankyrins
Phase 0 - rapid depolarisation
Drugs
Ranolazine
Valproic acid
Oxcarbazepine
Cocaine
Zonisamide
Brivaracetam
Dichlorobenzyl alcohol
Fish oil
Diseases
Brugada syndrome (BRS)
GWAS
Congenital heart disease (maternal effect) (
28468790
)
Major depressive disorder (
29317602
)
Metabolite levels (X-11787) (
23934736
)
Chronic lymphocytic leukemia (
28165464
24292274
23770605
)
Response to citalopram or escitalopram in depression (
27622933
)
Interacting Genes
61 interacting genes:
AQP2
AQP6
ASGR2
ATP6V0E1
BEST1
BIK
CBARP
CD79A
CLDN7
CREB3L1
CREB3L3
DAGLA
EBP
EDA
EREG
ERGIC3
EVA1A
FAM209A
FAM210B
FFAR2
GJA4
GJA5
GJA8
GJB1
GJB5
GJB6
GJC3
GPR152
HERPUD2
JSRP1
KCNMB4
KLRC1
LHFPL5
LRRC3B
MMGT1
MS4A3
NPDC1
ODF4
POMK
RAMP1
RHCG
RNF185
SCN3B
SLC12A7
SLC13A4
SLC16A2
SLC18A1
SLC30A2
SLC39A2
SLC7A1
SPAG4
SSMEM1
TBXA2R
TLCD4
TM4SF18
TMC4
TMEM14B
TMEM237
TMEM52B
TMEM74
VSIR
105 interacting genes:
ADIPOQ
AGPAT4
AGPAT5
ANKRD46
AQP10
ARV1
ATP13A1
ATP6V0C
BNIP1
BNIP3
BRICD5
CLCA4
CTXN3
CYP4F2
DEFB103A
DEFB103B
DERL1
DGAT2L6
ERG28
FAM241B
FAM3C
FIS1
FKBP8
FXYD3
GIMAP1
GIMAP5
GPR151
GPR61
IER3IP1
INSIG2
ISM2
ITGAM
LEMD1
LEPROTL1
LPAR3
MAL2
MARCHF2
MFSD5
MGST3
MS4A13
NFASC
NINJ2
ORMDL1
ORMDL2
PLBD2
PLP2
PLPPR2
PMP22
RHD
RNF8
RUSF1
SACM1L
SCD
SEC22A
SERP2
SFT2D1
SFXN1
SFXN3
SLC2A5
SLC30A3
SLC30A8
SLC35A4
SLC35E4
SLC38A1
SLC38A7
SLC7A1
SMCO4
SMIM1
STRIT1
STX3
STX6
STX8
THSD7A
TIMM23
TM6SF2
TMBIM6
TMEM120A
TMEM120B
TMEM128
TMEM140
TMEM14A
TMEM14B
TMEM208
TMEM239
TMEM243
TMEM42
TMEM50B
TMEM60
TMEM65
TMEM86A
TMPPE
TPRG1
TRARG1
TSPAN2
TVP23B
UBIAD1
USE1
VAMP1
VAMP2
VAMP3
VAPA
VAPB
YIF1A
YIPF4
ZFPL1
Entrez ID
503497
55800
HPRD ID
17604
10497
Ensembl ID
ENSG00000204979
ENSG00000166257
Uniprot IDs
Q5J8X5
A0A024R3H7
Q9NY72
PDB IDs
4L1D
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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