PAFAH1B3 and CHMP7

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PAFAH1B3	CHMP7
Description		platelet activating factor acetylhydrolase 1b catalytic subunit 3	charged multivesicular body protein 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol 1-alkyl-2-acetylglycerophosphocholine Esterase Complex Membrane	Chromatin ESCRT III Complex Nuclear Envelope Nucleoplasm Multivesicular Body Cytosol
	Molecular Function	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Protein Binding Identical Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding Protein Heterodimerization Activity Platelet-activating Factor Acetyltransferase Activity	Protein Binding
	Biological Process	Lipid Metabolic Process Spermatogenesis Nervous System Development Brain Development Lipid Catabolic Process	Vesicle Budding From Membrane Nucleus Organization Mitotic Metaphase Plate Congression Exit From Mitosis Protein Transport Endosomal Transport Viral Life Cycle Nuclear Envelope Reassembly Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Late Endosome To Vacuole Transport Midbody Abscission Protein Localization To Chromatin ESCRT III Complex Disassembly
Pathways		COPI-independent Golgi-to-ER retrograde traffic	Budding and maturation of HIV virion Macroautophagy Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs		(1R)-1,2,2-trimethylpropyl (R)-methylphosphinate
Diseases
GWAS			Attention deficit hyperactivity disorder ( 20732625) Brain morphology (MOSTest) ( 32665545) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		36 interacting genes: BRD7 CCDC90B CHMP7 COPS6 CRMP1 DDX24 ECH1 EEF1A1 ERG28 GAPDH GBP2 GDF9 HSPH1 IGSF21 LNX1 LRIF1 MED31 MEI4 NIF3L1 PAFAH1B1 PAFAH1B2 PICK1 PLEKHM1 RBM48 SDCBP2 SETDB1 SUMO4 TERF1 TERF2IP TLE1 TP53 TUBB2A UNC119 XRCC6 ZBTB16 ZHX1	5 interacting genes: CREB3 PAFAH1B3 TRIM55 TRIM63 USP8
Entrez ID		5050	91782
HPRD ID		04354	14534
Ensembl ID		ENSG00000079462	ENSG00000147457
Uniprot IDs		A0A024R0L6 Q15102	B3KMN6 B3KRZ9 B3KUH0 Q8WUX9
PDB IDs
Enriched GO Terms of Interacting Partners?
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