TIMM10B and PLD2

Data Source:
BioGRID (affinity chromatography technology)

		TIMM10B	PLD2
Description		translocase of inner mitochondrial membrane 10B	phospholipase D2
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GO Annotations	Cellular Component	Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Mitochondrial Intermembrane Space Protein Transporter Complex TIM22 Mitochondrial Import Inner Membrane Insertion Complex	Endoplasmic Reticulum Membrane Plasma Membrane Presynapse
	Molecular Function	Protein Binding Metal Ion Binding Protein Transporter Activity	Phospholipase D Activity Protein Binding Phosphatidylinositol Binding N-acylphosphatidylethanolamine-specific Phospholipase D Activity
	Biological Process	Protein Targeting To Mitochondrion Cell-matrix Adhesion Protein Insertion Into Mitochondrial Inner Membrane	Phosphatidic Acid Biosynthetic Process Cytoskeleton Organization Small GTPase Mediated Signal Transduction Lipid Catabolic Process Synaptic Vesicle Recycling Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Inositol Lipid-mediated Signaling Cell Motility
Pathways		Mitochondrial protein import	Synthesis of PG Synthesis of PA Role of phospholipids in phagocytosis
Drugs			Choline Choline salicylate
Diseases
GWAS		Malaria ( 31844061)	Sphingolipid levels ( 22359512) Systemic lupus erythematosus ( 26502338)
Interacting Genes		5 interacting genes: EIF3F HGS KLHL38 MBD3 MEIS2	29 interacting genes: ACTB ACTN1 ALDOA ALDOC AMPH AQP3 ARF1 BIN1 CAV1 CSK DPYSL2 EGFR FYN GAPDH GM2A HIF1A LCK MTDH MTOR OPRM1 PEA15 PIP5K1A PLCG1 PRKCA PRKCD RPTOR SRC STXBP1 VHL
Entrez ID		26515	5338
HPRD ID		16242	03857
Ensembl ID		ENSG00000132286	ENSG00000129219
Uniprot IDs		B2R4A9 Q9Y5J6	O14939
PDB IDs		7CGP	6OHM 6OHO 6OHP 6OHQ 6OHS
Enriched GO Terms of Interacting Partners?
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