CNNM3 and TGM1

Data Source:
BioGRID (two hybrid)

		CNNM3	TGM1
Description		cyclin and CBS domain divalent metal cation transport mediator 3	transglutaminase 1
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GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Cornified Envelope Cytosol Plasma Membrane Membrane Intrinsic Component Of Membrane Extracellular Exosome
	Molecular Function	Protein Binding Transmembrane Transporter Activity	Protein-glutamine Gamma-glutamyltransferase Activity Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Transport Ion Transport Transmembrane Transport	Cellular Protein Modification Process Positive Regulation Of Keratinocyte Proliferation Peptide Cross-linking Protein Phosphopantetheinylation Keratinocyte Differentiation Cell Envelope Organization Positive Regulation Of Cell Cycle Cornification
Pathways			Formation of the cornified envelope
Drugs
Diseases			Lamellar ichthyosis (LI) and Non-bullous congenital ichthyosiform erythroderma (NBCIE)
GWAS		Bipolar disorder ( 31043756) Birth weight ( 31043758) Erectile dysfunction and prostate cancer treatment ( 20932654) Offspring birth weight ( 31043758)
Interacting Genes		71 interacting genes: ACTN2 AGR2 AGR3 AKAP8L CALCOCO2 CARD10 CBY2 CCNDBP1 COG6 CYSRT1 EFEMP2 EXOSC8 FHL3 FHL5 GOLGA6L9 HNRNPK HOXA1 HSF2BP KHDRBS2 KHDRBS3 KPRP KRT31 KRT33B KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-3 KRTAP17-1 KRTAP2-4 KRTAP3-1 KRTAP3-2 KRTAP4-12 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LZTS2 MDFI MID2 MTUS2 NBPF19 NOTCH2NLA P4HB PM20D2 PNMA1 PNMA2 PNMA3 PTP4A2 RBMX RBMY1F RBMY1J RBPMS RELA SRSF3 SSC4D TGM1 TNS2 TRIM27 UBE2G2 UBQLN2 USHBP1 VWC2 WWOX ZNF330 ZRANB1	34 interacting genes: ACADL ALPP C1QTNF1 CNNM3 CRCT1 CXCL16 DOCK2 GSTP1 HSPB1 IFI30 IGSF8 ITGB4 JOSD1 KRTAP4-12 KRTAP5-9 LCE1B LCE1E LCE3A LCE4A MDK MYPOP NECTIN2 NUBP2 PLAAT4 RIN3 SCARF1 SEMG1 SEMG2 SNCA SULT4A1 TACC2 TRAPPC14 VASN VSTM4
Entrez ID		26505	7051
HPRD ID		07419	01824
Ensembl ID		ENSG00000168763	ENSG00000092295
Uniprot IDs		Q8NE01	P22735
PDB IDs		5K22 5K23 5K25 5TSR 6DFD 6MN6 6WUR	2XZZ
Enriched GO Terms of Interacting Partners?
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