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KAT2A and BECN1
Data Source:
BioGRID
(fluorescent resonance energy transfer)
KAT2A
BECN1
Description
lysine acetyltransferase 2A
beclin 1
Image
GO Annotations
Cellular Component
Histone Acetyltransferase Complex
Extracellular Space
Nucleus
Nucleoplasm
Ada2/Gcn5/Ada3 Transcription Activator Complex
Chromosome
Centrosome
STAGA Complex
Transcription Factor TFTC Complex
Oxoglutarate Dehydrogenase Complex
Mitotic Spindle
Phagophore Assembly Site
Nucleus
Mitochondrion
Endosome
Autophagosome
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Trans-Golgi Network
Cytosol
Endosome Membrane
Extrinsic Component Of Membrane
Dendrite
Mitochondrial Membrane
Phosphatidylinositol 3-kinase Complex, Class III, Type I
Phosphatidylinositol 3-kinase Complex, Class III, Type II
Phosphatidylinositol 3-kinase Complex, Class III
Phagocytic Vesicle
Molecular Function
Chromatin Binding
Transcription Coactivator Activity
Histone Acetyltransferase Activity
Protein Binding
Transcription Factor Binding
H3 Histone Acetyltransferase Activity
Protein Phosphatase Binding
Histone Deacetylase Binding
Histone Acetyltransferase Activity (H4-K12 Specific)
Peptide-lysine-N-acetyltransferase Activity
Histone Succinyltransferase Activity
Histone Glutaryltransferase Activity
Protein Binding
Protein Kinase Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Phosphatidylinositol 3-kinase Binding
GTPase Binding
Biological Process
In Utero Embryonic Development
Somitogenesis
Cytokine Production
Neural Tube Closure
Chromatin Remodeling
Regulation Of Transcription By RNA Polymerase II
Heart Development
Long-term Memory
Cell Population Proliferation
Response To Organic Cyclic Compound
Viral Process
Histone Acetylation
Histone Deubiquitination
Protein Deubiquitination
Protein Phosphopantetheinylation
Internal Peptidyl-lysine Acetylation
Telencephalon Development
Metencephalon Development
Midbrain Development
Positive Regulation Of Cell Projection Organization
Regulation Of Protein Stability
Response To Nutrient Levels
Positive Regulation Of Histone Acetylation
Multicellular Organism Growth
Histone H3 Acetylation
Histone H4-K12 Acetylation
Histone H3-K14 Acetylation
Regulation Of Regulatory T Cell Differentiation
Positive Regulation Of Gluconeogenesis
Positive Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Centriole Replication
Regulation Of Synaptic Plasticity
Intracellular Distribution Of Mitochondria
Regulation Of T Cell Activation
Limb Development
Regulation Of Cartilage Development
Cellular Response To Tumor Necrosis Factor
Alpha-tubulin Acetylation
Histone Succinylation
Peptidyl-lysine Glutarylation
Regulation Of Bone Development
Cellular Response To Nerve Growth Factor Stimulus
Regulation Of Stem Cell Population Maintenance
Positive Regulation Of Cardiac Muscle Cell Differentiation
Autophagosome Assembly
Autophagy Of Mitochondrion
Mitophagy
Response To Hypoxia
Autophagy
Apoptotic Process
Cellular Defense Response
Cellular Response To Nitrogen Starvation
Lysosome Organization
Mitotic Metaphase Plate Congression
Aging
Negative Regulation Of Cell Population Proliferation
Response To Iron(II) Ion
Response To Lead Ion
Positive Regulation Of Cardiac Muscle Hypertrophy
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Viral Process
Macroautophagy
Protein Deubiquitination
Regulation Of Cytokinesis
Receptor Catabolic Process
Response To Vitamin E
Cellular Response To Amino Acid Starvation
Cellular Response To Glucose Starvation
Response To Drug
Negative Regulation Of Apoptotic Process
Engulfment Of Apoptotic Cell
Early Endosome To Late Endosome Transport
Late Endosome To Vacuole Transport
Neuron Development
Amyloid-beta Metabolic Process
Regulation Of Catalytic Activity
Cell Division
Defense Response To Virus
Negative Regulation Of Cell Death
Cellular Response To Hydrogen Peroxide
Cellular Response To Aluminum Ion
Cellular Response To Copper Ion
Cellular Response To Epidermal Growth Factor Stimulus
Response To Mitochondrial Depolarisation
Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore
Negative Regulation Of Autophagosome Assembly
Negative Regulation Of Lysosome Organization
Negative Regulation Of Reactive Oxygen Species Metabolic Process
Positive Regulation Of Autophagosome Assembly
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Pre-NOTCH Transcription and Translation
Pre-NOTCH Transcription and Translation
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
NOTCH1 Intracellular Domain Regulates Transcription
NOTCH1 Intracellular Domain Regulates Transcription
Constitutive Signaling by NOTCH1 PEST Domain Mutants
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
HATs acetylate histones
Notch-HLH transcription pathway
B-WICH complex positively regulates rRNA expression
Ub-specific processing proteases
RNA Polymerase I Transcription Initiation
RUNX3 regulates NOTCH signaling
RUNX3 regulates NOTCH signaling
NOTCH3 Intracellular Domain Regulates Transcription
NOTCH3 Intracellular Domain Regulates Transcription
NOTCH4 Intracellular Domain Regulates Transcription
Macroautophagy
Ub-specific processing proteases
Translation of Replicase and Assembly of the Replication Transcription Complex
Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Coenzyme A
Estradiol
Estradiol acetate
Estradiol benzoate
Estradiol cypionate
Estradiol dienanthate
Estradiol valerate
Diseases
GWAS
Coronary artery disease (
29212778
33020668
)
Inflammatory bowel disease (
26278503
)
Mean reticulocyte volume (
32888494
)
Vitiligo (
27723757
)
vWF and FVIII levels (
30586737
)
Type 2 diabetes (age of onset) (
28060188
)
Interacting Genes
60 interacting genes:
AKT1
ATXN7
BATF2
BECN1
CCND2
CCNE1
CDK2
CDK6
CDKN2B
CEBPB
COMMD1
CREBBP
CRX
CTNNB1
CUL2
DTL
EID1
EP300
FZR1
GATA2
GRM1
H1-5
H2AC20
H2BC21
H3-4
H3C14
H4-16
H4C14
HSD11B2
IRF1
IRF2
IRF7
KDELR2
LATS2
MAP2K3
MAPK14
MYB
MYC
NF2
NOTCH1
PBX1
PPARG
PRKDC
PYGO2
RASSF1
RBPJ
RELA
SIRT2
STK11
TACC1
TACC2
TACC3
TADA2A
TCF3
TP53
TRRAP
TSC1
TTYH2
UBE2I
XRCC6
59 interacting genes:
AKT1
AMBRA1
ARAF
ARNT
ATG3
BCL2
BCL2L1
BCL2L10
BTK
CASP3
CCND2
CDK4
CDK6
CDKN2A
CDKN2B
EPHA2
ERBB2
FGFR4
FRS2
FZR1
GFI1B
GLIS2
GOPC
GRM1
HERC5
ITCH
ITPR1
ITPR3
KAT2A
KDELR2
LATS2
MAP2K3
MAP2K5
MAP2K6
MAPKAPK2
MAPKAPK3
MDM4
MST1
NF2
NXF1
PDGFRA
PGK1
RACK1
RAF1
SENP3
SGF29
SHD
SMAD2
STK11
STYK1
TEAD2
TERT
TRAF2
TSC1
UBC
ULK1
WASHC1
XPO1
YES1
Entrez ID
2648
8678
HPRD ID
03807
05087
Ensembl ID
ENSG00000108773
ENSG00000126581
Uniprot IDs
Q92830
A0A024R1X5
B4DQ36
E7EV84
Q14457
W0FFG4
PDB IDs
1F68
1Z4R
3D7C
5H84
5H86
5MLJ
5TRL
5TRM
6J3P
2P1L
2PON
3DVU
4DDP
4MI8
5EFM
5HHE
5VAU
5VAX
5VAY
6DCN
6DCO
6HOI
6HOJ
6HOK
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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