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KAT2A and TRRAP
Data Source:
BioGRID
(affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology)
HPRD
(in vitro, in vivo)
KAT2A
TRRAP
Description
lysine acetyltransferase 2A
transformation/transcription domain associated protein
Image
No pdb structure
GO Annotations
Cellular Component
Histone Acetyltransferase Complex
Extracellular Space
Nucleus
Nucleoplasm
Ada2/Gcn5/Ada3 Transcription Activator Complex
Chromosome
Centrosome
STAGA Complex
Transcription Factor TFTC Complex
Oxoglutarate Dehydrogenase Complex
Mitotic Spindle
SAGA Complex
PCAF Complex
Swr1 Complex
Nucleus
Nucleoplasm
Golgi Apparatus
STAGA Complex
Transcription Factor TFTC Complex
NuA4 Histone Acetyltransferase Complex
Molecular Function
Chromatin Binding
Transcription Coactivator Activity
Histone Acetyltransferase Activity
Protein Binding
Transcription Factor Binding
H3 Histone Acetyltransferase Activity
Protein Phosphatase Binding
Histone Deacetylase Binding
Histone Acetyltransferase Activity (H4-K12 Specific)
Peptide-lysine-N-acetyltransferase Activity
Histone Succinyltransferase Activity
Histone Glutaryltransferase Activity
Transcription Coregulator Activity
Protein Binding
Kinase Activity
Biological Process
In Utero Embryonic Development
Somitogenesis
Cytokine Production
Neural Tube Closure
Chromatin Remodeling
Regulation Of Transcription By RNA Polymerase II
Heart Development
Long-term Memory
Cell Population Proliferation
Response To Organic Cyclic Compound
Viral Process
Histone Acetylation
Histone Deubiquitination
Protein Deubiquitination
Protein Phosphopantetheinylation
Internal Peptidyl-lysine Acetylation
Telencephalon Development
Metencephalon Development
Midbrain Development
Positive Regulation Of Cell Projection Organization
Regulation Of Protein Stability
Response To Nutrient Levels
Positive Regulation Of Histone Acetylation
Multicellular Organism Growth
Histone H3 Acetylation
Histone H4-K12 Acetylation
Histone H3-K14 Acetylation
Regulation Of Regulatory T Cell Differentiation
Positive Regulation Of Gluconeogenesis
Positive Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Centriole Replication
Regulation Of Synaptic Plasticity
Intracellular Distribution Of Mitochondria
Regulation Of T Cell Activation
Limb Development
Regulation Of Cartilage Development
Cellular Response To Tumor Necrosis Factor
Alpha-tubulin Acetylation
Histone Succinylation
Peptidyl-lysine Glutarylation
Regulation Of Bone Development
Cellular Response To Nerve Growth Factor Stimulus
Regulation Of Stem Cell Population Maintenance
Positive Regulation Of Cardiac Muscle Cell Differentiation
DNA Repair
Regulation Of Transcription, DNA-templated
Phosphorylation
Histone Acetylation
Histone Deubiquitination
Protein Deubiquitination
Histone H4 Acetylation
Histone H2A Acetylation
Beta-catenin-TCF Complex Assembly
Pathways
Pre-NOTCH Transcription and Translation
Pre-NOTCH Transcription and Translation
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
NOTCH1 Intracellular Domain Regulates Transcription
NOTCH1 Intracellular Domain Regulates Transcription
Constitutive Signaling by NOTCH1 PEST Domain Mutants
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
HATs acetylate histones
Notch-HLH transcription pathway
B-WICH complex positively regulates rRNA expression
Ub-specific processing proteases
RNA Polymerase I Transcription Initiation
RUNX3 regulates NOTCH signaling
RUNX3 regulates NOTCH signaling
NOTCH3 Intracellular Domain Regulates Transcription
NOTCH3 Intracellular Domain Regulates Transcription
NOTCH4 Intracellular Domain Regulates Transcription
Formation of the beta-catenin:TCF transactivating complex
Formation of the beta-catenin:TCF transactivating complex
HATs acetylate histones
Ub-specific processing proteases
Drugs
Coenzyme A
Diseases
GWAS
Coronary artery disease (
29212778
33020668
)
Inflammatory bowel disease (
26278503
)
Mean reticulocyte volume (
32888494
)
Vitiligo (
27723757
)
vWF and FVIII levels (
30586737
)
Hemoglobin levels (
32327693
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
27863252
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Interacting Genes
60 interacting genes:
AKT1
ATXN7
BATF2
BECN1
CCND2
CCNE1
CDK2
CDK6
CDKN2B
CEBPB
COMMD1
CREBBP
CRX
CTNNB1
CUL2
DTL
EID1
EP300
FZR1
GATA2
GRM1
H1-5
H2AC20
H2BC21
H3-4
H3C14
H4-16
H4C14
HSD11B2
IRF1
IRF2
IRF7
KDELR2
LATS2
MAP2K3
MAPK14
MYB
MYC
NF2
NOTCH1
PBX1
PPARG
PRKDC
PYGO2
RASSF1
RBPJ
RELA
SIRT2
STK11
TACC1
TACC2
TACC3
TADA2A
TCF3
TP53
TRRAP
TSC1
TTYH2
UBE2I
XRCC6
18 interacting genes:
ACTL6A
ATXN7
AURKA
BRCA1
BRD8
CDC42
CTNNB1
E2F1
E2F4
EP400
ESR1
KAT2A
MAX
MRGBP
MYC
PYGO2
SKP1
TCF3
Entrez ID
2648
8295
HPRD ID
03807
04310
Ensembl ID
ENSG00000108773
ENSG00000196367
Uniprot IDs
Q92830
Q9Y4A5
PDB IDs
1F68
1Z4R
3D7C
5H84
5H86
5MLJ
5TRL
5TRM
6J3P
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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