TRRAP and MRGBP

Data Source:
HPRD (in vitro)

		TRRAP	MRGBP
Description		transformation/transcription domain associated protein	MRG domain binding protein
Image		No pdb structure
GO Annotations	Cellular Component	SAGA Complex PCAF Complex Swr1 Complex Nucleus Nucleoplasm Golgi Apparatus STAGA Complex Transcription Factor TFTC Complex NuA4 Histone Acetyltransferase Complex	Nucleoplasm NuA4 Histone Acetyltransferase Complex
	Molecular Function	Transcription Coregulator Activity Protein Binding Kinase Activity	Protein Binding
	Biological Process	DNA Repair Regulation Of Transcription, DNA-templated Phosphorylation Histone Acetylation Histone Deubiquitination Protein Deubiquitination Histone H4 Acetylation Histone H2A Acetylation Beta-catenin-TCF Complex Assembly	Regulation Of Transcription By RNA Polymerase II Histone Acetylation Regulation Of Growth
Pathways		Formation of the beta-catenin:TCF transactivating complex Formation of the beta-catenin:TCF transactivating complex HATs acetylate histones Ub-specific processing proteases	HATs acetylate histones
Drugs
Diseases
GWAS		Hemoglobin levels ( 32327693) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		18 interacting genes: ACTL6A ATXN7 AURKA BRCA1 BRD8 CDC42 CTNNB1 E2F1 E2F4 EP400 ESR1 KAT2A MAX MRGBP MYC PYGO2 SKP1 TCF3	25 interacting genes: ACTB ACTL6A BRD8 DAPK1 DMAP1 HSPB1 ING1 KRTAP1-1 KRTAP10-7 KRTAP17-1 KRTAP5-7 LRRK2 MEAF6 MFHAS1 MORF4L1 MORF4L2 MSL1 NBPF19 NOTCH2NLA RUVBL1 SH3BP4 TRRAP TUBB VAV2 YEATS4
Entrez ID		8295	55257
HPRD ID		04310	16646
Ensembl ID		ENSG00000196367	ENSG00000101189
Uniprot IDs		Q9Y4A5	Q9NV56
PDB IDs			2N1D
Enriched GO Terms of Interacting Partners?
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