TRRAP and BRD8

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, in vitro)

		TRRAP	BRD8
Description		transformation/transcription domain associated protein	bromodomain containing 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	SAGA Complex PCAF Complex Swr1 Complex Nucleus Nucleoplasm Golgi Apparatus STAGA Complex Transcription Factor TFTC Complex NuA4 Histone Acetyltransferase Complex	Swr1 Complex Nucleoplasm Mitochondrion NuA4 Histone Acetyltransferase Complex
	Molecular Function	Transcription Coregulator Activity Protein Binding Kinase Activity	Protein Binding Nuclear Receptor Coactivator Activity Thyroid Hormone Receptor Binding
	Biological Process	DNA Repair Regulation Of Transcription, DNA-templated Phosphorylation Histone Acetylation Histone Deubiquitination Protein Deubiquitination Histone H4 Acetylation Histone H2A Acetylation Beta-catenin-TCF Complex Assembly	Cell Surface Receptor Signaling Pathway Histone Acetylation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Thyroid Hormone Stimulus
Pathways		Formation of the beta-catenin:TCF transactivating complex Formation of the beta-catenin:TCF transactivating complex HATs acetylate histones Ub-specific processing proteases	HATs acetylate histones
Drugs
Diseases
GWAS		Hemoglobin levels ( 32327693) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)	Autism spectrum disorder or schizophrenia ( 28540026) Menarche (age at onset) ( 25231870)
Interacting Genes		18 interacting genes: ACTL6A ATXN7 AURKA BRCA1 BRD8 CDC42 CTNNB1 E2F1 E2F4 EP400 ESR1 KAT2A MAX MRGBP MYC PYGO2 SKP1 TCF3	12 interacting genes: AGTR1 EP400 FSD2 MCRS1 MIS18A MRGBP PIN1 PPARG RXRA THRB TRRAP WEE1
Entrez ID		8295	10902
HPRD ID		04310	04166
Ensembl ID		ENSG00000196367	ENSG00000112983
Uniprot IDs		Q9Y4A5	B4DEG9 B4DMS9 B4DN43 Q9H0E9
PDB IDs
Enriched GO Terms of Interacting Partners?
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