TRRAP and EP400

Data Source:
HPRD (in vivo, in vitro)

		TRRAP	EP400
Description		transformation/transcription domain associated protein	E1A binding protein p400
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	SAGA Complex PCAF Complex Swr1 Complex Nucleus Nucleoplasm Golgi Apparatus STAGA Complex Transcription Factor TFTC Complex NuA4 Histone Acetyltransferase Complex	Swr1 Complex Nucleoplasm Nuclear Speck NuA4 Histone Acetyltransferase Complex
	Molecular Function	Transcription Coregulator Activity Protein Binding Kinase Activity	DNA Binding Chromatin Binding Helicase Activity Protein Binding ATP Binding Protein Antigen Binding
	Biological Process	DNA Repair Regulation Of Transcription, DNA-templated Phosphorylation Histone Acetylation Histone Deubiquitination Protein Deubiquitination Histone H4 Acetylation Histone H2A Acetylation Beta-catenin-TCF Complex Assembly	Histone H4 Acetylation Histone H2A Acetylation
Pathways		Formation of the beta-catenin:TCF transactivating complex Formation of the beta-catenin:TCF transactivating complex HATs acetylate histones Ub-specific processing proteases	Formation of Senescence-Associated Heterochromatin Foci (SAHF) DNA Damage/Telomere Stress Induced Senescence HATs acetylate histones
Drugs
Diseases
GWAS		Hemoglobin levels ( 32327693) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)	Body mass index ( 26426971) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 27863252 28957414)
Interacting Genes		18 interacting genes: ACTL6A ATXN7 AURKA BRCA1 BRD8 CDC42 CTNNB1 E2F1 E2F4 EP400 ESR1 KAT2A MAX MRGBP MYC PYGO2 SKP1 TCF3	13 interacting genes: ALAS1 BRD8 KAT5 MNS1 MYC NTAQ1 POLR1C RAD51 SUMO2 TBC1D4 TRAF2 TRRAP ZGPAT
Entrez ID		8295	57634
HPRD ID		04310	09378
Ensembl ID		ENSG00000196367	ENSG00000183495
Uniprot IDs		Q9Y4A5	Q96L91
PDB IDs
Enriched GO Terms of Interacting Partners?
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