SERBP1 and UBA2

Data Source:
HPRD (two hybrid, in vivo)

		SERBP1	UBA2
Description		SERPINE1 mRNA binding protein 1	ubiquitin like modifier activating enzyme 2
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Nucleoplasm Cytoplasm SUMO Activating Enzyme Complex
	Molecular Function	RNA Binding MRNA 3'-UTR Binding Protein Binding SUMO Binding Cadherin Binding	Magnesium Ion Binding Protein Binding ATP Binding Transcription Factor Binding Transferase Activity SUMO Activating Enzyme Activity SUMO Binding Small Protein Activating Enzyme Binding Ubiquitin-like Protein Conjugating Enzyme Binding Protein Heterodimerization Activity
	Biological Process	PML Body Organization Regulation Of Apoptotic Process Regulation Of MRNA Stability	Protein Sumoylation Protein Phosphopantetheinylation Protein Modification By Small Protein Conjugation Positive Regulation Of Protein Sumoylation
Pathways			SUMO is conjugated to E1 (UBA2:SAE1) SUMO is conjugated to E1 (UBA2:SAE1) SUMO is transferred from E1 to E2 (UBE2I, UBC9) SUMO is transferred from E1 to E2 (UBE2I, UBC9)
Drugs
Diseases
GWAS		Bone mineral density (hip) ( 30172743) Carotid plaque burden ( 28282560) Crohn's disease ( 28067908 22412388) Inflammatory bowel disease ( 28067908) Primary biliary cholangitis ( 26394269) Ulcerative colitis ( 28067908)
Interacting Genes		21 interacting genes: - APP CHD3 CSNK2A1 DAXX ESR1 FBXO25 FXYD3 KAT2B PIAS1 PIAS3 PIAS4 PICK1 PRMT8 TDG TERT TOPORS UBA2 UPF2 VAV2 VIM	17 interacting genes: BRIX1 CHEK1 ERCC6 ETV4 MEOX2 NEDD8 PARK7 RAD23B SAE1 SERBP1 SUMO1 SUMO1P1 SUMO2 SUMO3 UBC UBD UBE2I
Entrez ID		26135	10054
HPRD ID		09570	11658
Ensembl ID		ENSG00000142864	ENSG00000126261
Uniprot IDs		Q5VU21 Q63HR1 Q8NC51	Q9UBT2
PDB IDs		4V6X 6Z6M 6Z6N	1Y8Q 1Y8R 2PX9 3KYC 3KYD 4W5V 5FQ2 6CWY 6CWZ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?