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UBA2 and SUMO3
Data Source:
HPRD
(in vitro, in vivo)
UBA2
SUMO3
Description
ubiquitin like modifier activating enzyme 2
small ubiquitin like modifier 3
Image
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
SUMO Activating Enzyme Complex
Kinetochore
Nucleus
Nucleoplasm
Cytoplasm
PML Body
Molecular Function
Magnesium Ion Binding
Protein Binding
ATP Binding
Transcription Factor Binding
Transferase Activity
SUMO Activating Enzyme Activity
SUMO Binding
Small Protein Activating Enzyme Binding
Ubiquitin-like Protein Conjugating Enzyme Binding
Protein Heterodimerization Activity
Protein Binding
Protein Tag
Ubiquitin-like Protein Ligase Binding
Biological Process
Protein Sumoylation
Protein Phosphopantetheinylation
Protein Modification By Small Protein Conjugation
Positive Regulation Of Protein Sumoylation
Protein Sumoylation
Negative Regulation Of DNA Binding
Regulation Of Protein Localization To Nucleus
Pathways
SUMO is conjugated to E1 (UBA2:SAE1)
SUMO is conjugated to E1 (UBA2:SAE1)
SUMO is transferred from E1 to E2 (UBE2I, UBC9)
SUMO is transferred from E1 to E2 (UBE2I, UBC9)
SUMO is conjugated to E1 (UBA2:SAE1)
SUMO is transferred from E1 to E2 (UBE2I, UBC9)
SUMO is proteolytically processed
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription factors
SUMOylation of transcription cofactors
SUMOylation of intracellular receptors
SUMOylation of intracellular receptors
SUMOylation of chromatin organization proteins
SUMOylation of DNA replication proteins
SUMOylation of immune response proteins
Formation of Incision Complex in GG-NER
Drugs
Diseases
GWAS
Delirium (
29631748
)
Interacting Genes
17 interacting genes:
BRIX1
CHEK1
ERCC6
ETV4
MEOX2
NEDD8
PARK7
RAD23B
SAE1
SERBP1
SUMO1
SUMO1P1
SUMO2
SUMO3
UBC
UBD
UBE2I
53 interacting genes:
ANXA7
BLM
CCNE2
CDKN1A
CEBPA
CHAF1A
CUL3
DAXX
EGLN3
FAM221A
FOS
HIPK2
HOMEZ
HSF1
HSF2
JUN
KALRN
MAPKAPK3
PFDN1
PIAS1
PIAS2
PIAS3
PIAS4
PML
RANGAP1
RNF111
RNF8
SAE1
SENP1
SENP2
SENP5
SMN1
SOX10
SOX6
SP100
TDG
TDP2
TK1
TP53BP2
TTR
UBA2
UBE2I
UBE3A
UPF2
USP25
USPL1
VIM
WWTR1
YAP1
ZBTB33
ZBTB39
ZCCHC12
ZNF496
Entrez ID
10054
6612
HPRD ID
11658
03754
Ensembl ID
ENSG00000126261
ENSG00000184900
Uniprot IDs
Q9UBT2
P55854
PDB IDs
1Y8Q
1Y8R
2PX9
3KYC
3KYD
4W5V
5FQ2
6CWY
6CWZ
1U4A
2IO1
2MP2
6K5R
6NNQ
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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