SERBP1 and FXYD3

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SERBP1	FXYD3
Description		SERPINE1 mRNA binding protein 1	FXYD domain containing ion transport regulator 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome
	Molecular Function	RNA Binding MRNA 3'-UTR Binding Protein Binding SUMO Binding Cadherin Binding	Chloride Channel Activity Sodium Channel Regulator Activity Ion Channel Regulator Activity
	Biological Process	PML Body Organization Regulation Of Apoptotic Process Regulation Of MRNA Stability	Potassium Ion Transport Sodium Ion Transport Chloride Transport Ion Transmembrane Transport Chloride Transmembrane Transport Regulation Of Cardiac Conduction Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways			Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS
Drugs
Diseases
GWAS		Bone mineral density (hip) ( 30172743) Carotid plaque burden ( 28282560) Crohn's disease ( 28067908 22412388) Inflammatory bowel disease ( 28067908) Primary biliary cholangitis ( 26394269) Ulcerative colitis ( 28067908)
Interacting Genes		21 interacting genes: - APP CHD3 CSNK2A1 DAXX ESR1 FBXO25 FXYD3 KAT2B PIAS1 PIAS3 PIAS4 PICK1 PRMT8 TDG TERT TOPORS UBA2 UPF2 VAV2 VIM	64 interacting genes: AGR3 ANK1 AQP6 AQP9 BCL2L13 BEST2 CD79A CNR2 CREB3 CREB3L1 CYB5R3 EBP ERG28 ERGIC3 FAM209A FBXL12 FCGR2A FFAR2 GHITM GPR152 GPR37L1 GPR42 GPRC5D IBSP KASH5 KCNN4 LMNA LTC4S MAPK6 MFSD11 MFSD5 MGST1 MTIF3 NR4A1 NUDT3 PLPP6 SCN3B SERBP1 SGPL1 SLC10A1 SLC10A6 SLC16A12 SLC18A1 SLC1A1 SLC30A2 SLC35A1 SLC35B1 SLC35C2 SLC39A2 SPNS3 STRIT1 STX3 TIMM23 TIMMDC1 TLCD1 TMBIM6 TMEM179B TMEM50B TMEM52B TMEM80 TMEM86A TMEM97 TSPO2 XKR3
Entrez ID		26135	5349
HPRD ID		09570	05410
Ensembl ID		ENSG00000142864	ENSG00000089356
Uniprot IDs		Q5VU21 Q63HR1 Q8NC51	Q14802
PDB IDs		4V6X 6Z6M 6Z6N
Enriched GO Terms of Interacting Partners?
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