UBA2 and BRIX1

		UBA2	BRIX1
Description		ubiquitin like modifier activating enzyme 2	biogenesis of ribosomes BRX1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm SUMO Activating Enzyme Complex	Chromosome Nucleolus
	Molecular Function	Magnesium Ion Binding Protein Binding ATP Binding Transcription Factor Binding Transferase Activity SUMO Activating Enzyme Activity SUMO Binding Small Protein Activating Enzyme Binding Ubiquitin-like Protein Conjugating Enzyme Binding Protein Heterodimerization Activity	RNA Binding Protein Binding
	Biological Process	Protein Sumoylation Protein Phosphopantetheinylation Protein Modification By Small Protein Conjugation Positive Regulation Of Protein Sumoylation	Ribosomal Large Subunit Assembly
Pathways		SUMO is conjugated to E1 (UBA2:SAE1) SUMO is conjugated to E1 (UBA2:SAE1) SUMO is transferred from E1 to E2 (UBE2I, UBC9) SUMO is transferred from E1 to E2 (UBE2I, UBC9)
Drugs
Diseases
GWAS
Interacting Genes		17 interacting genes: BRIX1 CHEK1 ERCC6 ETV4 MEOX2 NEDD8 PARK7 RAD23B SAE1 SERBP1 SUMO1 SUMO1P1 SUMO2 SUMO3 UBC UBD UBE2I	6 interacting genes: CD48 EBNA1BP2 GSK3B SETDB1 UBA2 UNC119
Entrez ID		10054	55299
HPRD ID		11658	16563
Ensembl ID		ENSG00000126261	ENSG00000113460
Uniprot IDs		Q9UBT2	Q8TDN6
PDB IDs		1Y8Q 1Y8R 2PX9 3KYC 3KYD 4W5V 5FQ2 6CWY 6CWZ
Enriched GO Terms of Interacting Partners?
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