SERBP1 and PRMT8

Data Source:
BioGRID (two hybrid)

		SERBP1	PRMT8
Description		SERPINE1 mRNA binding protein 1	protein arginine methyltransferase 8
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Nucleus Plasma Membrane Anchored Component Of The Cytoplasmic Side Of The Plasma Membrane
	Molecular Function	RNA Binding MRNA 3'-UTR Binding Protein Binding SUMO Binding Cadherin Binding	Protein Binding Histone-arginine N-methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity Enzyme Binding Protein-arginine Omega-N Monomethyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Identical Protein Binding Protein Homodimerization Activity S-adenosyl-L-methionine Binding
	Biological Process	PML Body Organization Regulation Of Apoptotic Process Regulation Of MRNA Stability	Protein Methylation Histone Methylation Peptidyl-arginine Methylation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Histone Arginine Methylation Regulation Of Protein Binding Protein Homooligomerization
Pathways
Drugs
Diseases
GWAS		Bone mineral density (hip) ( 30172743) Carotid plaque burden ( 28282560) Crohn's disease ( 28067908 22412388) Inflammatory bowel disease ( 28067908) Primary biliary cholangitis ( 26394269) Ulcerative colitis ( 28067908)	Cardiac Troponin-T levels ( 31014085) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Gut microbiota (bacterial taxa) ( 27723756) HDL cholesterol ( 19060911)
Interacting Genes		21 interacting genes: - APP CHD3 CSNK2A1 DAXX ESR1 FBXO25 FXYD3 KAT2B PIAS1 PIAS3 PIAS4 PICK1 PRMT8 TDG TERT TOPORS UBA2 UPF2 VAV2 VIM	22 interacting genes: CARM1 CEP162 COIL DCAF8 EWSR1 FBL FYN GPATCH2L H4C1 KRTAP6-3 OFCC1 PIK3R1 PLCG1 PPARA PRMT1 PRMT2 SERBP1 SYNCRIP TNPO2 UBL5 VHL ZNF451
Entrez ID		26135	56341
HPRD ID		09570	11029
Ensembl ID		ENSG00000142864	ENSG00000111218
Uniprot IDs		Q5VU21 Q63HR1 Q8NC51	Q59GT2 Q9NR22
PDB IDs		4V6X 6Z6M 6Z6N	4X41 5DST
Enriched GO Terms of Interacting Partners?
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