GPSM1 and OSTM1

Data Source:
BioGRID (pull down)

		GPSM1	OSTM1
Description		G protein signaling modulator 1	osteoclastogenesis associated transmembrane protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Cell Cortex Protein-containing Complex	Lysosomal Membrane Cytosol Integral Component Of Membrane
	Molecular Function	GDP-dissociation Inhibitor Activity Protein Binding
	Biological Process	Nervous System Development Positive Regulation Of Macroautophagy Cell Differentiation Negative Regulation Of GTPase Activity Negative Regulation Of Guanyl-nucleotide Exchange Factor Activity	Osteoclast Differentiation Ion Transmembrane Transport
Pathways		G alpha (i) signalling events	Stimuli-sensing channels
Drugs
Diseases			Osteopetrosis, including: Osteopetrosis, severe neonatal or infantile forms; Osteopetrosis, intermediate forms; Osteopetrosis with renal tubular acidosis; Osteopetrosis, late-onset form type 1; Osteopetrosis, late-onset form type 2; Osteopetrosis, osteoclast poor
GWAS		Acute insulin response (insulin secretion adjusted) ( 28490609) Birth weight ( 31043758) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Insulinogenic index ( 23263489) Joint damage in rheumatoid arthritis ( 26498133) Offspring birth weight ( 31043758) Type 2 diabetes ( 30297969 29632382 26818947 23945395 31118516 32499647 30718926 28869590) Type 2 diabetes (adjusted for BMI) ( 29632382) Ulcerative colitis ( 28067908) White blood cell count ( 29403010)	Major depressive disorder ( 29187746)
Interacting Genes		26 interacting genes: BHLHE40 CCDC158 DAZAP2 DCAF11 DMRT3 FAM161B FAM83A FAM90A1 GCM2 GLIS2 GNAI1 GNAI3 HMG20A INSC KANK2 MAP1LC3A OSTM1 RIBC1 SEPTIN1 TASOR2 TEKT4 TRIP13 USHBP1 USP9X VEZF1 ZBED1	6 interacting genes: CLCN7 GPSM1 LIG4 RGS17 RGS19 RGS20
Entrez ID		26086	28962
HPRD ID		17075	09628
Ensembl ID		ENSG00000160360	ENSG00000081087
Uniprot IDs		A0A087WVF5 A0A0A0MRC4 A0A0A0MSK4 Q86YR5	Q86WC4
PDB IDs			7BXU 7JM7
Enriched GO Terms of Interacting Partners?
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