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WWTR1 and TEAD4
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
WWTR1
TEAD4
Description
WW domain containing transcription regulator 1
TEA domain transcription factor 4
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Transcription Regulator Complex
Cytoplasm
Cytosol
Plasma Membrane
Nuclear Body
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Molecular Function
Transcription Coactivator Activity
Transcription Corepressor Activity
Protein Binding
Protein Homodimerization Activity
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Osteoblast Differentiation
Tissue Homeostasis
Negative Regulation Of Protein Phosphorylation
Heart Process
Regulation Of Transcription, DNA-templated
Transcription Initiation From RNA Polymerase II Promoter
Negative Regulation Of Protein Kinase Activity
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of Epithelial To Mesenchymal Transition
Protein Ubiquitination
Stem Cell Division
SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Glomerulus Development
Multicellular Organism Growth
Hippo Signaling
Negative Regulation Of Fat Cell Differentiation
Positive Regulation Of Osteoblast Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Mesenchymal Cell Differentiation
Cilium Assembly
Regulation Of SMAD Protein Signal Transduction
Kidney Morphogenesis
Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation
Negative Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Protein Localization To Nucleus
Skeletal System Development
Regulation Of Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Muscle Organ Development
Hippo Signaling
Embryonic Organ Development
Pathways
Signaling by Hippo
YAP1- and WWTR1 (TAZ)-stimulated gene expression
YAP1- and WWTR1 (TAZ)-stimulated gene expression
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Physiological factors
RUNX2 regulates osteoblast differentiation
RUNX3 regulates YAP1-mediated transcription
EGR2 and SOX10-mediated initiation of Schwann cell myelination
YAP1- and WWTR1 (TAZ)-stimulated gene expression
RUNX3 regulates YAP1-mediated transcription
Drugs
Diseases
GWAS
Height (
31562340
)
Polycystic ovary syndrome (
32289280
)
Preeclampsia (
23551011
)
Narcolepsy with cataplexy (
23496005
)
Interacting Genes
22 interacting genes:
C1orf74
DAPK1
IL16
LATS1
LATS2
MFHAS1
NKX2-1
PAX3
PPP1CA
RTN4IP1
RUNX1
SLC9A3R2
SUMO3
TCP11L1
TEAD1
TEAD2
TEAD3
TEAD4
WBP2
YWHAE
YWHAG
YWHAZ
50 interacting genes:
CCDC125
CCDC172
CCDC85B
CCNDBP1
CDR2
CEP55
CEP70
CTBP1
DYDC1
EXOC3-AS1
FBXO7
GOLGA2
GOLGA6L9
HAUS1
HOMEZ
INCA1
KIAA0753
KRT27
KRT31
KRT40
KRTAP10-3
LDOC1
LZTS2
MDFI
MTUS2
MYH7
NUTM1
PDE4DIP
PFKM
PNMA1
PRDM14
PRKAR1B
RABGEF1
RASSF10
RUNDC3A
RUNX1
SAT1
SESTD1
SORBS3
SSX2IP
TLE5
TRAF1
TRIM27
TRIM54
VGLL1
VGLL3
VPS52
VTA1
WWTR1
YAP1
Entrez ID
25937
7004
HPRD ID
09580
03421
Ensembl ID
ENSG00000018408
ENSG00000197905
Uniprot IDs
Q9GZV5
Q15561
PDB IDs
5N5R
5N5T
5N5W
5N75
6RHC
6RJL
6RJQ
6RP6
6SLW
6SLX
5GZB
5NO6
5OAQ
6GE3
6GE4
6GE5
6GE6
6GEC
6GEE
6GEG
6GEI
6GEK
6HIK
6Q2X
6Q36
6SEN
6SEO
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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