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WWTR1 and IL16
Data Source:
BioGRID
(two hybrid)
WWTR1
IL16
Description
WW domain containing transcription regulator 1
interleukin 16
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Transcription Regulator Complex
Cytoplasm
Cytosol
Plasma Membrane
Nuclear Body
Extracellular Region
Extracellular Space
Cytosol
Plasma Membrane
Focal Adhesion
Nuclear Speck
Flemming Body
Molecular Function
Transcription Coactivator Activity
Transcription Corepressor Activity
Protein Binding
Protein Homodimerization Activity
Cytokine Activity
CD4 Receptor Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Osteoblast Differentiation
Tissue Homeostasis
Negative Regulation Of Protein Phosphorylation
Heart Process
Regulation Of Transcription, DNA-templated
Transcription Initiation From RNA Polymerase II Promoter
Negative Regulation Of Protein Kinase Activity
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of Epithelial To Mesenchymal Transition
Protein Ubiquitination
Stem Cell Division
SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Glomerulus Development
Multicellular Organism Growth
Hippo Signaling
Negative Regulation Of Fat Cell Differentiation
Positive Regulation Of Osteoblast Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Mesenchymal Cell Differentiation
Cilium Assembly
Regulation Of SMAD Protein Signal Transduction
Kidney Morphogenesis
Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation
Negative Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Protein Localization To Nucleus
Immune Response
Viral Process
Cytokine-mediated Signaling Pathway
Leukocyte Chemotaxis
Positive Regulation Of Interleukin-1 Alpha Production
Positive Regulation Of Interleukin-12 Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Inflammatory Response
Induction Of Positive Chemotaxis
Regulation Of Calcium Ion Transport
Pathways
Signaling by Hippo
YAP1- and WWTR1 (TAZ)-stimulated gene expression
YAP1- and WWTR1 (TAZ)-stimulated gene expression
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Physiological factors
RUNX2 regulates osteoblast differentiation
RUNX3 regulates YAP1-mediated transcription
EGR2 and SOX10-mediated initiation of Schwann cell myelination
Other interleukin signaling
Drugs
Diseases
GWAS
Height (
31562340
)
Polycystic ovary syndrome (
32289280
)
Preeclampsia (
23551011
)
Blood protein levels (
30072576
29875488
28240269
)
Blood protein levels in cardiovascular risk (
28369058
)
Body mass index (
26426971
)
Brown vs. black hair color (
30531825
)
Colorectal cancer (aspirin and/or NSAID use interaction) (
25781442
)
Height (
31562340
)
Inattentive symptoms (
18821565
)
Interleukin-16 levels (
27989323
)
Lymphocyte counts (
32888494
)
Monocyte count (
32888494
)
Primary biliary cholangitis (
28425483
)
Interacting Genes
22 interacting genes:
C1orf74
DAPK1
IL16
LATS1
LATS2
MFHAS1
NKX2-1
PAX3
PPP1CA
RTN4IP1
RUNX1
SLC9A3R2
SUMO3
TCP11L1
TEAD1
TEAD2
TEAD3
TEAD4
WBP2
YWHAE
YWHAG
YWHAZ
108 interacting genes:
ANXA6
BLZF1
BOLA2
BOLA2B
CALCOCO2
CAMK1
CARD10
CASP3
CCDC184
CCDC33
CD4
CDK1
CEP72
CSNK2A1
CSNK2A2
CYSRT1
DMRTB1
DUSP7
EFEMP2
FAM124A
FHL2
FHL5
FTO
GABPB1
GOLGA2
GOLGA6L9
GRIN2A
GRIN2B
GRIN2C
GRIN2D
HDAC3
HOMEZ
HOOK2
HSF2BP
JAKMIP1
KANK2
KCNA3
KCND1
KCND2
KCNJ10
KCNJ15
KCNJ2
KCNJ4
KCTD9
KDM1A
KIF16B
KIFC3
KRT31
KRT86
KRTAP1-1
KRTAP1-3
KRTAP10-8
KRTAP3-1
L3MBTL3
LGALS14
LMO3
LNX1
LNX2
MBD3L1
MID2
MIER2
MTUS2
MYOG
NOXA1
NTAQ1
OIP5
PDLIM7
PFDN5
PICK1
PPP1R12A
PPP1R12B
PPP1R12C
PPP1R16A
PRDM6
PRR13
PSTPIP1
RAPGEF2
RBCK1
RNF144B
SERTAD3
SMARCB1
SOHLH1
SPRED1
SUV39H1
TEPSIN
TFIP11
TRIB3
TRIM23
TRIM27
TRIM42
TRIP6
UBXN11
USHBP1
WWTR1
ZBTB39
ZIM2
ZNF143
ZNF165
ZNF474
ZNF526
ZNF572
ZNF581
ZNF620
ZNF774
ZNF777
ZNF835
ZNRD2
ZRANB1
Entrez ID
25937
3603
HPRD ID
09580
04329
Ensembl ID
ENSG00000018408
ENSG00000172349
Uniprot IDs
Q9GZV5
Q14005
Q9UME6
PDB IDs
5N5R
5N5T
5N5W
5N75
6RHC
6RJL
6RJQ
6RP6
6SLW
6SLX
1I16
1X6D
5FB8
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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