TEAD4 and VTA1

Data Source:
BioGRID (two hybrid)

		TEAD4	VTA1
Description		TEA domain transcription factor 4	vesicle trafficking 1
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex	Nucleoplasm Multivesicular Body Cytosol Endosome Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding	Protein Binding Protein C-terminus Binding
	Biological Process	Skeletal System Development Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Muscle Organ Development Hippo Signaling Embryonic Organ Development	Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Multivesicular Body Sorting Pathway ESCRT III Complex Disassembly
Pathways		YAP1- and WWTR1 (TAZ)-stimulated gene expression RUNX3 regulates YAP1-mediated transcription	Budding and maturation of HIV virion Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases
GWAS		Narcolepsy with cataplexy ( 23496005)	Chronic obstructive pulmonary disease ( 30804561) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) FEV1 ( 30804560) Height ( 28552196) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Peak expiratory flow ( 30804560) Response to radiotherapy in nasopharyngeal carcinoma (acute oral mucositis) ( 32503578) Retinal vascular caliber ( 21060863)
Interacting Genes		50 interacting genes: CCDC125 CCDC172 CCDC85B CCNDBP1 CDR2 CEP55 CEP70 CTBP1 DYDC1 EXOC3-AS1 FBXO7 GOLGA2 GOLGA6L9 HAUS1 HOMEZ INCA1 KIAA0753 KRT27 KRT31 KRT40 KRTAP10-3 LDOC1 LZTS2 MDFI MTUS2 MYH7 NUTM1 PDE4DIP PFKM PNMA1 PRDM14 PRKAR1B RABGEF1 RASSF10 RUNDC3A RUNX1 SAT1 SESTD1 SORBS3 SSX2IP TLE5 TRAF1 TRIM27 TRIM54 VGLL1 VGLL3 VPS52 VTA1 WWTR1 YAP1	22 interacting genes: APP BEX3 CBS CCNC CDK4 CHMP1A CHMP1B CHMP5 DPPA2 ERBB3 KCTD13 KLHL12 LYST MAGEA11 MBIP NBR1 NECAB2 RABAC1 RPIA TEAD4 ZBTB16 ZNRD2
Entrez ID		7004	51534
HPRD ID		03421	09855
Ensembl ID		ENSG00000197905	ENSG00000009844
Uniprot IDs		Q15561	A0A087WY55 Q9NP79
PDB IDs		5GZB 5NO6 5OAQ 6GE3 6GE4 6GE5 6GE6 6GEC 6GEE 6GEG 6GEI 6GEK 6HIK 6Q2X 6Q36 6SEN 6SEO	2LXL 2LXM 4TXP 4TXQ 4TXR 4U7E
Enriched GO Terms of Interacting Partners?
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