IL16 and LGALS14

Data Source:
BioGRID (two hybrid)

		IL16	LGALS14
Description		interleukin 16	galectin 14
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytosol Plasma Membrane Focal Adhesion Nuclear Speck Flemming Body	Nucleoplasm
	Molecular Function	Cytokine Activity CD4 Receptor Binding	Protein Binding Carbohydrate Binding
	Biological Process	Immune Response Viral Process Cytokine-mediated Signaling Pathway Leukocyte Chemotaxis Positive Regulation Of Interleukin-1 Alpha Production Positive Regulation Of Interleukin-12 Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Inflammatory Response Induction Of Positive Chemotaxis Regulation Of Calcium Ion Transport	Apoptotic Process Positive Regulation Of T Cell Apoptotic Process
Pathways		Other interleukin signaling
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Blood protein levels in cardiovascular risk ( 28369058) Body mass index ( 26426971) Brown vs. black hair color ( 30531825) Colorectal cancer (aspirin and/or NSAID use interaction) ( 25781442) Height ( 31562340) Inattentive symptoms ( 18821565) Interleukin-16 levels ( 27989323) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Primary biliary cholangitis ( 28425483)	Sum eosinophil basophil counts ( 27863252)
Interacting Genes		108 interacting genes: ANXA6 BLZF1 BOLA2 BOLA2B CALCOCO2 CAMK1 CARD10 CASP3 CCDC184 CCDC33 CD4 CDK1 CEP72 CSNK2A1 CSNK2A2 CYSRT1 DMRTB1 DUSP7 EFEMP2 FAM124A FHL2 FHL5 FTO GABPB1 GOLGA2 GOLGA6L9 GRIN2A GRIN2B GRIN2C GRIN2D HDAC3 HOMEZ HOOK2 HSF2BP JAKMIP1 KANK2 KCNA3 KCND1 KCND2 KCNJ10 KCNJ15 KCNJ2 KCNJ4 KCTD9 KDM1A KIF16B KIFC3 KRT31 KRT86 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP3-1 L3MBTL3 LGALS14 LMO3 LNX1 LNX2 MBD3L1 MID2 MIER2 MTUS2 MYOG NOXA1 NTAQ1 OIP5 PDLIM7 PFDN5 PICK1 PPP1R12A PPP1R12B PPP1R12C PPP1R16A PRDM6 PRR13 PSTPIP1 RAPGEF2 RBCK1 RNF144B SERTAD3 SMARCB1 SOHLH1 SPRED1 SUV39H1 TEPSIN TFIP11 TRIB3 TRIM23 TRIM27 TRIM42 TRIP6 UBXN11 USHBP1 WWTR1 ZBTB39 ZIM2 ZNF143 ZNF165 ZNF474 ZNF526 ZNF572 ZNF581 ZNF620 ZNF774 ZNF777 ZNF835 ZNRD2 ZRANB1	46 interacting genes: ADAMTSL4 AJUBA BANP BLZF1 C1QTNF2 COG6 CRLF3 DDIT4L DOK6 FCHO1 FLACC1 FLNA GFAP IKZF3 IL16 JRK KRT19 KRT35 LNX1 LNX2 MEI4 MID2 NFKBID PCBD2 PICK1 POF1B PPM1J REL RIMBP3C SDCBP2 SH3GLB2 SPAG5 STAT5B TARS3 TBC1D25 TCF4 TEKT1 TEPSIN TNR TRIM23 TRIM27 VIM ZBTB8A ZNF438 ZNF655 ZNF71
Entrez ID		3603	56891
HPRD ID		04329	06268
Ensembl ID		ENSG00000172349	ENSG00000006659
Uniprot IDs		Q14005 Q9UME6	Q8TCE9
PDB IDs		1I16 1X6D 5FB8	6K2Y 6K2Z
Enriched GO Terms of Interacting Partners?
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