CBX1 and EMSY

Data Source:
HPRD (in vitro, in vivo)

		CBX1	EMSY
Description		chromobox 1	EMSY transcriptional repressor, BRCA2 interacting
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromosome, Telomeric Region Chromatin Heterochromatin Female Pronucleus Male Pronucleus Nucleus Nucleoplasm Pericentric Heterochromatin Spindle Chromocenter Site Of DNA Damage	Nucleoplasm
	Molecular Function	Chromatin Binding Protein Binding Enzyme Binding Identical Protein Binding Histone Methyltransferase Binding	Protein Binding Identical Protein Binding
	Biological Process	Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription, DNA-templated	DNA Repair Chromatin Organization Regulation Of Transcription, DNA-templated
Pathways		HCMV Early Events
Drugs
Diseases
GWAS		Body mass index ( 26426971 20935630) Generalized epilepsy ( 22949513)	Allergic rhinitis ( 31361310) Asthma ( 31361310 31959851 29273806) Asthma (adult onset) ( 31036433) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Eczema ( 31361310) Eosinophil counts ( 29403010)
Interacting Genes		36 interacting genes: ABI3BP ARL5A ATXN7L2 BAHD1 BARD1 BRCA1 CBX3 CBX5 CHAF1A DNMT1 DNMT3A DNMT3B EMSY H1-4 H3-4 H3C1 H3C3 HECW2 HSPB1 KLF11 LNX1 LRIF1 NR2F6 NSL1 PCNA PIM1 RB1 RPL12 SP100 SUV39H1 TRIM24 TRIM28 UCHL1 VHL VTN ZNF280C	14 interacting genes: AIDA AKT1 BRCA2 CBX1 CLVS2 DDIT3 DISC1 GET3 H3-4 LIX1 PSMA1 ZMYND11 ZNF131 ZNF646
Entrez ID		10951	56946
HPRD ID		05149	10544
Ensembl ID		ENSG00000108468	ENSG00000158636
Uniprot IDs		P83916 Q6IBN6	Q7Z589
PDB IDs		2FMM 3F2U 3Q6S 5T1G 6D07 6D08	1UTU 1UZ3 2FMM
Enriched GO Terms of Interacting Partners?
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