POLR1A and POLR1E

Data Source:
HPRD (in vitro)

		POLR1A	POLR1E
Description		RNA polymerase I subunit A	RNA polymerase I subunit E
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Chromosome RNA Polymerase I Complex	Fibrillar Center Nucleoplasm Nucleolus RNA Polymerase I Complex
	Molecular Function	RNA Polymerase I Activity DNA Binding Chromatin Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Zinc Ion Binding	RNA Polymerase I General Transcription Initiation Factor Binding DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding
	Biological Process	Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Positive Regulation Of Gene Expression, Epigenetic Negative Regulation Of Protein Localization To Nucleolus	RNA Polymerase I Preinitiation Complex Assembly Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Nucleolar Large RRNA Transcription By RNA Polymerase I Positive Regulation Of Gene Expression, Epigenetic
Pathways		NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination	NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS		Facial emotion recognition (sad faces) ( 28608620)
Interacting Genes		10 interacting genes: ANP32B DYDC2 MEOX2 NFKBIB NOLC1 POLR1E PTEN REL RRN3 TCF4	8 interacting genes: NFKBIB POLR1A POLR1B POLR1C POLR1G SIRT7 TAF1C UBTF
Entrez ID		25885	64425
HPRD ID		10161	15096
Ensembl ID		ENSG00000068654	ENSG00000137054
Uniprot IDs		O95602	B4E005 Q9GZS1
PDB IDs
Enriched GO Terms of Interacting Partners?
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