POLR1A and DYDC2

Data Source:
BioGRID (two hybrid)

		POLR1A	DYDC2
Description		RNA polymerase I subunit A	DPY30 domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Chromosome RNA Polymerase I Complex	Chromosome, Telomeric Region MLL3/4 Complex Set1C/COMPASS Complex
	Molecular Function	RNA Polymerase I Activity DNA Binding Chromatin Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Zinc Ion Binding	Protein Binding
	Biological Process	Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Positive Regulation Of Gene Expression, Epigenetic Negative Regulation Of Protein Localization To Nucleolus	Chromatin Silencing At Telomere Histone H3-K4 Methylation
Pathways		NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS		Facial emotion recognition (sad faces) ( 28608620)	Estimated glomerular filtration rate ( 31451708) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848)
Interacting Genes		10 interacting genes: ANP32B DYDC2 MEOX2 NFKBIB NOLC1 POLR1E PTEN REL RRN3 TCF4	5 interacting genes: DPY30 NME5 POLR1A TENT5D UBXN2A
Entrez ID		25885	84332
HPRD ID		10161	11311
Ensembl ID		ENSG00000068654	ENSG00000133665
Uniprot IDs		O95602	A0A0A0MRQ7 Q96IM9
PDB IDs
Enriched GO Terms of Interacting Partners?
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