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NR5A1 and TBX19
Data Source:
HPRD
(in vitro)
NR5A1
TBX19
Description
nuclear receptor subfamily 5 group A member 1
T-box transcription factor 19
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Cytosol
RNA Polymerase II Transcription Regulator Complex
Chromatin
Nucleus
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA Binding
Chromatin Binding
Nuclear Receptor Activity
Protein Binding
Phospholipid Binding
Zinc Ion Binding
Enzyme Binding
Sequence-specific DNA Binding
Sequence-specific Double-stranded DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Luteinization
Regulation Of Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Sex Determination
Primary Sex Determination
Male Gonad Development
Female Gonad Development
Hormone-mediated Signaling Pathway
Tissue Development
Multicellular Organism Aging
Positive Regulation Of Gene Expression
Cell Differentiation
Male Sex Determination
Adrenal Gland Development
Intracellular Receptor Signaling Pathway
Hormone Metabolic Process
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Steroid Biosynthetic Process
Maintenance Of Protein Location In Nucleus
Response To Gonadotropin-releasing Hormone
Calcineurin-mediated Signaling
Positive Regulation Of Male Gonad Development
Negative Regulation Of Female Gonad Development
Mesoderm Formation
Cell Fate Specification
Somitogenesis
Heart Morphogenesis
Regulation Of Transcription By RNA Polymerase II
Anatomical Structure Morphogenesis
Pituitary Gland Development
Regulation Of Cell Population Proliferation
Regulation Of Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Nuclear Receptor transcription pathway
SUMOylation of intracellular receptors
Transcriptional regulation of pluripotent stem cells
Transcriptional regulation of testis differentiation
Drugs
(2R)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(9E)-HEXADEC-9-ENOYLOXY]PROPYL (9E)-OCTADEC-9-ENOATE
Phosphatidyl ethanol
Diseases
Premature ovarian failure
46,XY disorders of sex development (Disorders of gonadal development), including: Gonadal agenesis; Complete and partial gonadal dysgenesis; Testis regression; Ovotesticular DSD
Adrenocorticotropic hormone deficiency; Isolated ACDH deficiency (IAD)
GWAS
Chronotype (
30696823
)
Interacting Genes
35 interacting genes:
AR
C2CD6
CKS1B
CREBBP
CTNNB1
CXXC1
EDF1
GATA4
GTF2B
JUN
MAPK1
NCK2
NCOA1
NFKB2
NFYA
NR0B1
NRIP1
NTAQ1
PIAS1
PITX1
PNRC2
PROX1
RAD54L2
RFC5
SMARCD3
SOX2
SOX8
SOX9
SP1
TBX19
TEKT4
TRAPPC2
TRERF1
UBE2I
ZNF653
15 interacting genes:
GCM2
HGS
HOXC8
IRX6
LONRF1
NEDD9
NR5A1
PITX1
POGZ
PRR35
RAB2B
TBX6
TFG
VENTX
ZIC1
Entrez ID
2516
9095
HPRD ID
01702
05214
Ensembl ID
ENSG00000136931
ENSG00000143178
Uniprot IDs
F1D8R8
Q13285
B3KRD9
O60806
PDB IDs
1YOW
1ZDT
4QJR
4QK4
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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