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NR5A1 and RAD54L2
Data Source:
BioGRID
(pull down)
NR5A1
RAD54L2
Description
nuclear receptor subfamily 5 group A member 1
RAD54 like 2
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Cytosol
RNA Polymerase II Transcription Regulator Complex
Nucleus
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA Binding
Chromatin Binding
Nuclear Receptor Activity
Protein Binding
Phospholipid Binding
Zinc Ion Binding
Enzyme Binding
Sequence-specific DNA Binding
Sequence-specific Double-stranded DNA Binding
DNA Binding
DNA Helicase Activity
Protein Binding
ATP Binding
Biological Process
Luteinization
Regulation Of Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Sex Determination
Primary Sex Determination
Male Gonad Development
Female Gonad Development
Hormone-mediated Signaling Pathway
Tissue Development
Multicellular Organism Aging
Positive Regulation Of Gene Expression
Cell Differentiation
Male Sex Determination
Adrenal Gland Development
Intracellular Receptor Signaling Pathway
Hormone Metabolic Process
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Steroid Biosynthetic Process
Maintenance Of Protein Location In Nucleus
Response To Gonadotropin-releasing Hormone
Calcineurin-mediated Signaling
Positive Regulation Of Male Gonad Development
Negative Regulation Of Female Gonad Development
DNA Duplex Unwinding
Pathways
Nuclear Receptor transcription pathway
SUMOylation of intracellular receptors
Transcriptional regulation of pluripotent stem cells
Transcriptional regulation of testis differentiation
Drugs
(2R)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(9E)-HEXADEC-9-ENOYLOXY]PROPYL (9E)-OCTADEC-9-ENOATE
Phosphatidyl ethanol
Diseases
Premature ovarian failure
46,XY disorders of sex development (Disorders of gonadal development), including: Gonadal agenesis; Complete and partial gonadal dysgenesis; Testis regression; Ovotesticular DSD
GWAS
Chronotype (
30696823
)
Estimated glomerular filtration rate (
31152163
)
Interacting Genes
35 interacting genes:
AR
C2CD6
CKS1B
CREBBP
CTNNB1
CXXC1
EDF1
GATA4
GTF2B
JUN
MAPK1
NCK2
NCOA1
NFKB2
NFYA
NR0B1
NRIP1
NTAQ1
PIAS1
PITX1
PNRC2
PROX1
RAD54L2
RFC5
SMARCD3
SOX2
SOX8
SOX9
SP1
TBX19
TEKT4
TRAPPC2
TRERF1
UBE2I
ZNF653
40 interacting genes:
AR
ATN1
ATXN1
ATXN1L
BANP
BHLHE40
CBX3
FAM118B
HMG20A
HNRNPCL1
HOMER1
IMPDH1
KIFC3
KRTAP6-3
LCE1D
LCE1F
NR3C1
NR5A1
NR5A2
PAICS
PIAS1
POU1F1
PPARG
PSMA3
RBPMS
RUNX1T1
RXRA
SIAH1
SQSTM1
SUMO1
SUMO2
TAX1BP1
TFAP2D
THAP1
TRAF2
TRAF4
UBE2I
VCX
ZBTB26
ZC2HC1A
Entrez ID
2516
23132
HPRD ID
01702
10018
Ensembl ID
ENSG00000136931
ENSG00000164080
Uniprot IDs
F1D8R8
Q13285
B3KV54
Q9Y4B4
PDB IDs
1YOW
1ZDT
4QJR
4QK4
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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