STAB1 and GGA3

Data Source:
BioGRID (pull down)

		STAB1	GGA3
Description		stabilin 1	golgi associated, gamma adaptin ear containing, ARF binding protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Endocytic Vesicle Membrane	Lysosome Golgi Apparatus Trans-Golgi Network Endosome Membrane Early Endosome Membrane Protein-containing Complex Recycling Endosome Membrane
	Molecular Function	Low-density Lipoprotein Particle Receptor Activity Scavenger Receptor Activity Calcium Ion Binding Protein Binding Hyaluronic Acid Binding Protein Disulfide Oxidoreductase Activity Low-density Lipoprotein Particle Binding	Protein Binding Small GTPase Binding Ubiquitin Binding Protein-containing Complex Binding
	Biological Process	Receptor-mediated Endocytosis Inflammatory Response Cell Adhesion Cell-cell Signaling Negative Regulation Of Angiogenesis Defense Response To Bacterium	Protein Targeting To Lysosome Intracellular Protein Transport Regulation Of Protein Stability Protein Destabilization Endocytic Recycling Protein Localization To Cell Surface Golgi To Plasma Membrane Protein Transport Cellular Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Negative Regulation Of Amyloid-beta Formation
Pathways		Scavenging by Class H Receptors	TBC/RABGAPs MET receptor recycling Amyloid fiber formation
Drugs
Diseases
GWAS		Adiponectin levels ( 31178129) Apolipoprotein A1 levels ( 32203549) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972 31043756) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) Cortical surface area (MOSTest) ( 32665545) Diverticular disease ( 30177863) HDL cholesterol ( 24097068) HDL cholesterol levels ( 28334899) Height ( 31562340) Hematocrit ( 27863252) Intelligence (MTAG) ( 29326435) Parkinson's disease ( 28892059) Schizophrenia ( 25056061 29483656 23974872) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urinary albumin-to-creatinine ratio ( 31511532) Waist-hip ratio ( 20935629) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		6 interacting genes: CHID1 GGA1 GGA2 GGA3 ORC5 PIK3R2	38 interacting genes: ADRA2A ADRA2B AFTPH AP1S2 ARAP3 ARF1 ARF3 CDKN2A CLINT1 CLTC CYTH2 DAZAP2 EGFR GGA1 GGA2 IGF2R LITAF LRP10 M6PR P4HA3 PACS1 PLEKHB2 RABEP1 RNF11 RNF214 RPS27A STAB1 SYNRG TBC1D3 TOLLIP TRAPPC6A TRIM23 TSG101 UBC UPRT VPS11 VPS18 ZNF497
Entrez ID		23166	23163
HPRD ID		09778	10443
Ensembl ID		ENSG00000010327	ENSG00000125447
Uniprot IDs		Q9NY15	A8K6M0 B7Z456 Q9NZ52
PDB IDs			1JPL 1JUQ 1LF8 1P4U 1WR6 1YD8
Enriched GO Terms of Interacting Partners?
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