CAND2 and DNAJB6

Data Source:
BioGRID (two hybrid)

		CAND2	DNAJB6
Description		cullin associated and neddylation dissociated 2 (putative)	DnaJ heat shock protein family (Hsp40) member B6
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	Nucleus Nucleoplasm Cytosol Membrane Z Disc Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding TBP-class Protein Binding	ATPase Activator Activity Protein Binding Heat Shock Protein Binding Unfolded Protein Binding Chaperone Binding
	Biological Process	SCF Complex Assembly Protein Ubiquitination Positive Regulation Of Transcription, DNA-templated	Protein Folding Positive Regulation Of ATPase Activity Regulation Of Protein Localization Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Intermediate Filament Organization Negative Regulation Of Inclusion Body Assembly Regulation Of Cellular Response To Heat
Pathways			Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS		Atrial fibrillation ( 30061737 29892015) Creatine kinase levels ( 29403010) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) HOMA-B (corrected for HOMA-IR) ( 30369944) P wave duration ( 28794112) Waist circumference adjusted for body mass index ( 28552196) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Body mass index ( 28552196) Retinal detachment or retinal break ( 31816047) Waist circumference ( 28552196)
Interacting Genes		9 interacting genes: CIDEB CNOT3 DNAJB6 FHL2 GLP1R RBX1 SYP TBP UBE3C	23 interacting genes: ANKRD1 APP ASAP1 BRMS1 CAND2 DYSF KRT18 MAP3K1 MLF1 MLF2 MRTO4 MYBPC1 MYOM1 PGM1 PIK3CA POLR1D PTEN SGCG SKAP2 SUPT6H TTN TUBGCP3 USP8
Entrez ID		23066	10049
HPRD ID		19120	07107
Ensembl ID		ENSG00000144712	ENSG00000105993
Uniprot IDs		O75155	A0A0J9YX62 O75190
PDB IDs			6U3R 6U3S
Enriched GO Terms of Interacting Partners?
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