DNAJB6 and SUPT6H

Data Source:
BioGRID (two hybrid)

		DNAJB6	SUPT6H
Description		DnaJ heat shock protein family (Hsp40) member B6	SPT6 homolog, histone chaperone and transcription elongation factor
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Membrane Z Disc Perinuclear Region Of Cytoplasm	Nucleoplasm Transcription Elongation Factor Complex Transcriptionally Active Chromatin
	Molecular Function	ATPase Activator Activity Protein Binding Heat Shock Protein Binding Unfolded Protein Binding Chaperone Binding	DNA Binding RNA Binding Protein Binding Nucleosome Binding Histone Binding
	Biological Process	Protein Folding Positive Regulation Of ATPase Activity Regulation Of Protein Localization Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Intermediate Filament Organization Negative Regulation Of Inclusion Body Assembly Regulation Of Cellular Response To Heat	Blastocyst Formation Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter MRNA Processing RNA Splicing Regulation Of MRNA Export From Nucleus Viral Process Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Nucleosome Organization MRNA Transcription By RNA Polymerase II Regulation Of Isotype Switching Regulation Of MRNA Processing MRNA Transport Regulation Of Muscle Cell Differentiation Negative Regulation Of Histone H3-K27 Methylation Chromatin Maintenance
Pathways		Regulation of HSF1-mediated heat shock response	Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Body mass index ( 28552196) Retinal detachment or retinal break ( 31816047) Waist circumference ( 28552196)	Pulse pressure ( 30578418)
Interacting Genes		23 interacting genes: ANKRD1 APP ASAP1 BRMS1 CAND2 DYSF KRT18 MAP3K1 MLF1 MLF2 MRTO4 MYBPC1 MYOM1 PGM1 PIK3CA POLR1D PTEN SGCG SKAP2 SUPT6H TTN TUBGCP3 USP8	13 interacting genes: AKT1 CSNK2A1 DNAJB6 EGFR ERBB2 ERCC6 GAB1 HSP90B1 HSPA9 HSPD1 IWS1 MCPH1 TSC2
Entrez ID		10049	6830
HPRD ID		07107	03211
Ensembl ID		ENSG00000105993	ENSG00000109111
Uniprot IDs		A0A0J9YX62 O75190	Q7KZ85
PDB IDs		6U3R 6U3S	6GME 6GMH 6TED
Enriched GO Terms of Interacting Partners?
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