DNAJB6 and CAND2

Data Source:
BioGRID (two hybrid)

		DNAJB6	CAND2
Description		DnaJ heat shock protein family (Hsp40) member B6	cullin associated and neddylation dissociated 2 (putative)
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Membrane Z Disc Perinuclear Region Of Cytoplasm	Nucleus Cytosol
	Molecular Function	ATPase Activator Activity Protein Binding Heat Shock Protein Binding Unfolded Protein Binding Chaperone Binding	Protein Binding TBP-class Protein Binding
	Biological Process	Protein Folding Positive Regulation Of ATPase Activity Regulation Of Protein Localization Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Intermediate Filament Organization Negative Regulation Of Inclusion Body Assembly Regulation Of Cellular Response To Heat	SCF Complex Assembly Protein Ubiquitination Positive Regulation Of Transcription, DNA-templated
Pathways		Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS		Body mass index ( 28552196) Retinal detachment or retinal break ( 31816047) Waist circumference ( 28552196)	Atrial fibrillation ( 30061737 29892015) Creatine kinase levels ( 29403010) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) HOMA-B (corrected for HOMA-IR) ( 30369944) P wave duration ( 28794112) Waist circumference adjusted for body mass index ( 28552196) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		23 interacting genes: ANKRD1 APP ASAP1 BRMS1 CAND2 DYSF KRT18 MAP3K1 MLF1 MLF2 MRTO4 MYBPC1 MYOM1 PGM1 PIK3CA POLR1D PTEN SGCG SKAP2 SUPT6H TTN TUBGCP3 USP8	9 interacting genes: CIDEB CNOT3 DNAJB6 FHL2 GLP1R RBX1 SYP TBP UBE3C
Entrez ID		10049	23066
HPRD ID		07107	19120
Ensembl ID		ENSG00000105993	ENSG00000144712
Uniprot IDs		A0A0J9YX62 O75190	O75155
PDB IDs		6U3R 6U3S
Enriched GO Terms of Interacting Partners?
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