LRSAM1 and MAGEA1

Data Source:
BioGRID (two hybrid)

		LRSAM1	MAGEA1
Description		leucine rich repeat and sterile alpha motif containing 1	MAGE family member A1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane	Nucleus Cytoplasm Plasma Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Histone Deacetylase Binding
	Biological Process	Protein Polyubiquitination Autophagy Protein Catabolic Process Negative Regulation Of Endocytosis Viral Budding Protein Autoubiquitination Ubiquitin-dependent Endocytosis Positive Regulation Of Xenophagy Positive Regulation Of Autophagosome Assembly	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Notch Signaling Pathway
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Mean corpuscular volume ( 32888494)
Interacting Genes		42 interacting genes: ATXN1 ATXN7 CCDC6 DMAP1 FAM178B GABARAPL2 GPR108 GRIK5 GSK3A KLC1 MAGEA1 MDM4 MGAT4B MKRN3 MUTYH MYL2 NINL PHF23 RNF111 RXRG TERF1 TNFRSF10C TRIM17 TRIM74 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2H UBE2I UBE2J1 UBE2K UBE2N UBE2W UEVLD USP2 USP21 VPS11 XAF1 ZMAT4	25 interacting genes: ABI2 CEP57L1 DNM1L HDAC1 HLA-A HLA-B HYPK LRSAM1 MDM4 MIEF1 NOTCH1 PBX3 PCGF6 RAB17 RNF166 S100A9 SELPLG SFN SGK1 SH3GLB2 SHFL SNW1 TRIM31 UQCRB ZNF564
Entrez ID		90678	4100
HPRD ID		14325	02059
Ensembl ID		ENSG00000148356	ENSG00000198681
Uniprot IDs		A0A024R870 Q6UWE0	P43355
PDB IDs			1W72 3BO8
Enriched GO Terms of Interacting Partners?
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