CCDC146 and KRT86

Data Source:
BioGRID (two hybrid)

		CCDC146	KRT86
Description		coiled-coil domain containing 146	keratin 86
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centriole Cytoskeleton	Extracellular Space Cytosol Keratin Filament
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Keratinization Cornification
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases			Monilethrix
GWAS		Body mass index ( 28892062) Response to amphetamines ( 22952603)	Blond vs. brown/black hair color ( 30531825) Diffusing capacity of carbon monoxide ( 30694715) Diisocyanate-induced asthma ( 25918132) Plasma amyloid beta peptide concentrations (ABx-42) ( 24535457)
Interacting Genes		71 interacting genes: AKAP9 BLOC1S2 CBY2 CCDC136 CCDC197 CCNDBP1 CDR2 CDR2L CENPH CEP170P1 CEP44 DTNBP1 FSD2 GAS8 GMNN GOLGA2 GOLGA6L9 GPRASP2 GRAMD4 HSF2BP INSYN1 KIFC3 KRT16 KRT18 KRT19 KRT24 KRT26 KRT27 KRT31 KRT34 KRT38 KRT40 KRT86 LHX3 MAGEA11 MAGEA6 MCC MED4 MIPOL1 MRFAP1 MTUS2 N4BP3 NAP1L2 NECAB2 NINL NUP62 PDE4DIP PLEKHF2 PNMA1 PPP2R3C PROSER3 PSMC6 RINT1 RNF40 RPGRIP1 SH3BP1 SYCE1L TEPSIN TFIP11 THOC7 TNR TPM3 TRAF1 TRIM23 TRIM54 TRIML2 TSC22D4 TXLNA USHBP1 VPS28 VPS52	45 interacting genes: CAMK2B CCDC146 CDK18 CEP57 CREB5 CYSRT1 GNE HGS HSD3B7 IL16 JOSD1 KANK2 KRT14 KRT15 KRT16 KRT19 KRT25 KRT27 KRT28 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRT76 MAPKBP1 MEOX2 MGAT5B MKRN3 NUTF2 ODF1 OIP5 OLIG3 RESF1 RTP5 SHC3 TEKT4 TSGA10IP ZNF414 ZNF655
Entrez ID		57639	3892
HPRD ID		11150	03567
Ensembl ID		ENSG00000135205	ENSG00000170442
Uniprot IDs		Q8IYE0 Q96MS1	A8K872 O43790
PDB IDs
Enriched GO Terms of Interacting Partners?
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