EPN2 and MLANA

Data Source:
BioGRID (two hybrid)

		EPN2	MLANA
Description		epsin 2	melan-A
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Cytosol Plasma Membrane Clathrin Vesicle Coat Clathrin Coat Of Endocytic Vesicle Intracellular Membrane-bounded Organelle	Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Integral Component Of Plasma Membrane Melanosome
	Molecular Function	Protein Binding Phospholipid Binding Clathrin Binding Cadherin Binding	Protein Binding
	Biological Process	Endocytosis Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Notch Signaling Pathway Membrane Organization Negative Regulation Of Sprouting Angiogenesis
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Diastolic blood pressure ( 30224653) White matter hyperintensities ( 32358547)	Asthma ( 31959851 31619474) Hippocampal volume in mild cognitive impairment ( 29274321) Multiple sclerosis ( 22190364)
Interacting Genes		40 interacting genes: APOE ARRDC1 ARRDC2 ARRDC3 ATXN1 CDIP1 CLTC DAZAP2 EIF3E EPS15 FAIM2 FAM168A FANCM ITSN1 LAPTM5 LITAF MID1 MID2 MLANA PIP4P1 PLEKHB2 PMEPA1 PRKAA2 RNF11 RNF8 SMAD1 SPART TFAP2A THOP1 TRIM23 TRIM26 TRIM62 TUBA1B TXLNA UBA52 UBC WBP1 WBP1L WBP2 YWHAG	3 interacting genes: EPN2 ITCH NEDD4
Entrez ID		22905	2315
HPRD ID		06271	09269
Ensembl ID		ENSG00000072134	ENSG00000120215
Uniprot IDs		O95208	A0A384MR46 Q16655
PDB IDs			2GT9 2GTW 2GTZ 2GUO 3HG1 3L6F 3MRO 3MRP 3MRQ 3QDM 3QEQ 3QFD 4EUP 4JFF 4L3E 4QOK 4WJ5 5E9D 5NHT 5NQK 6D78 6DKP
Enriched GO Terms of Interacting Partners?
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