TMEM130 and TSPAN2

Data Source:
BioGRID (two hybrid)

		TMEM130	TSPAN2
Description		transmembrane protein 130	tetraspanin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Integral Component Of Plasma Membrane	Nucleoplasm Integral Component Of Plasma Membrane Integral Component Of Membrane Myelin Sheath
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Inflammatory Response Brain Development Astrocyte Development Microglia Development Myelination Oligodendrocyte Differentiation Axon Development
Pathways
Drugs
Diseases
GWAS		Decreased low contrast letter acuity in multiple sclerosis ( 31289819)	Dysmenorrheic pain ( 27454463) Ischemic stroke (large artery atherosclerosis) ( 26708676 29531354) Large artery stroke (CCS and TOAST classification) ( 32047268) Large artery stroke (CCS or TOAST classification) ( 32047268) Large artery stroke (CCSp classification)j ( 32047268) Migraine ( 27182965 23793025 27322543) Migraine without aura ( 23793025 27322543)
Interacting Genes		10 interacting genes: GRM2 MFSD5 NKG7 OLFM4 PIGF SLC2A5 SLC35B4 TMEM100 TSPAN2 YIPF6	35 interacting genes: ABHD16A ATP1B4 BSCL2 CD79A CLDN5 CLEC14A CREB3 CREB3L1 DCBLD2 FAM209A FKBP7 FOS GRB2 IFNGR2 KDELR3 LEPROTL1 LMNA MFF MGST3 PGRMC2 PIK3R3 RABGAP1L REEP4 RNF19B SCN3B SLC10A6 SLC30A8 SLC35C2 TMEM130 TMEM14B TMEM31 TMX2 TSPAN31 VSIR ZFYVE27
Entrez ID		222865	10100
HPRD ID		13226	18233
Ensembl ID		ENSG00000166448	ENSG00000134198
Uniprot IDs		Q8N3G9	B1AKP1 B2RD31 O60636
PDB IDs
Enriched GO Terms of Interacting Partners?
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