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EWSR1 and WWP1
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
EWSR1
WWP1
Description
EWS RNA binding protein 1
WW domain containing E3 ubiquitin protein ligase 1
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Plasma Membrane
Ubiquitin Ligase Complex
Nucleus
Cytoplasm
Cytosol
Plasma Membrane
Extracellular Exosome
Molecular Function
Transcription Coregulator Activity
RNA Binding
Protein Binding
Calmodulin Binding
Identical Protein Binding
Metal Ion Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Ubiquitin Protein Ligase Activity
Biological Process
Regulation Of Transcription, DNA-templated
Protein Polyubiquitination
Signal Transduction
Central Nervous System Development
Protein Ubiquitination
Ion Transmembrane Transport
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Protein Catabolic Process
Negative Regulation Of Transcription, DNA-templated
Viral Entry Into Host Cell
Pathways
Downregulation of ERBB4 signaling
Stimuli-sensing channels
Regulation of RUNX2 expression and activity
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
Ewing's sarcoma
Myxoid liposarcoma
Clear cell sarcoma of soft tissue
Extraskeletal myxoid chondrosarcoma
GWAS
Breast cancer (
23535729
)
Pancreatic cancer (
25086665
)
Platelet count (
27863252
)
Platelet distribution width (
32888494
)
Estimated glomerular filtration rate (
31152163
)
Interacting Genes
162 interacting genes:
ACTL6A
AGT
ANXA11
ARID1A
ATN1
ATPAF2
ATXN3
BAD
BARD1
BLZF1
BNIP3L
BRME1
BTK
C11orf16
CALM1
CCDC7
CCDC91
CD177
CDK12
CEACAM5
CETP
CFDP1
CHERP
CNST
CPSF6
CPSF7
CREBBP
CUEDC2
CXADR
DFFA
DMRTB1
DNAJB3
DYNLL2
E2F8
ECD
ELAVL3
ELAVL4
ELK1
EPAS1
ERCC5
FAM131C
FASN
FLI1
FUS
FXR2
GNPDA1
GPBP1L1
H2BC15
HBP1
HDAC3
HERPUD1
HLTF
HMGA1
HMGN4
HNRNPUL1
HSPA2
IRF3
ITCH
ITGB5
JUN
KCNMB1
KEL
KHDRBS2
KRR1
KXD1
LILRA3
MAGEA11
MAPK1IP1L
MATK
MDFI
MNS1
MRPS18B
MSC
MTCP1
MTMR9
MVK
MYL6
MYO1F
MYOZ2
NBPF3
NDRG1
NDUFB1
NDUFV1
NINL
NLE1
NONO
NPPB
NSUN4
NTNG2
PCBP1
PDHX
PEF1
PGLS
PLSCR1
POLR2G
POLR3A
POU4F1
POU5F1
PRKCA
PRMT1
PRMT8
PRR13
PRRC2A
PRTFDC1
PRUNE2
PTK2B
RAB37
RAD23A
RALYL
RASL11B
RBPMS
RFX3
RHOXF2
RMND5B
RNF183
RPL31
RPS15A
SALL2
SCMH1
SEC24A
SEC24D
SELENOI
SERP2
SF1
SF3B4
SLC1A1
SLC22A24
SMAD1
SMAD4
SMARCC1
SMARCC2
SNRPC
SSBP2
SSBP3
SUPT4H1
SUV39H2
TAF1
TFG
TMSB4Y
TONSL
TPGS2
TRAF1
TRAF2
TRAF3
TRIM37
TRIM5
TRPV5
TSPAN3
TULP2
USP7
VPS72
WBP4
WDR37
WWP1
WWP2
YWHAG
YY1AP1
ZBTB1
ZDHHC3
ZNF165
ZNF184
ZNF383
55 interacting genes:
ARRDC1
ARRDC2
ARRDC3
ASH2L
ATN1
CLCN5
CPSF6
DAG1
DAZAP2
DIDO1
EWSR1
FAM189A2
FBXL18
HSPB1
IKBKG
IL2RG
IL6R
KLF2
KLF5
LAPTM5
LATS1
LNX1
LZTR1
MACROH2A2
MIR19A
MIR19B1
NFE2
NOTCH1
PCBD1
PHF20L1
PRKAA2
PYGM
RASA1
RNF11
RTN4
RUNX1
SCNN1A
SFTPC
SMAD3
SMAD5
STAT6
TFAP2A
TGIF1
TP53BP2
TRAF4
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2L3
WASL
WBP1
WBP2
YWHAQ
ZNF638
Entrez ID
2130
11059
HPRD ID
00592
03811
Ensembl ID
ENSG00000182944
ENSG00000123124
Uniprot IDs
Q01844
Q9H0M0
PDB IDs
2CPE
1ND7
2OP7
5HPS
5HPT
6J1X
6J1Y
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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