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EWSR1 and NONO
Data Source:
BioGRID
(two hybrid)
EWSR1
NONO
Description
EWS RNA binding protein 1
non-POU domain containing octamer binding
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Plasma Membrane
Fibrillar Center
Nucleus
Nucleoplasm
Membrane
Nuclear Matrix
Nuclear Speck
Paraspeckles
RNA Polymerase II Transcription Regulator Complex
Molecular Function
Transcription Coregulator Activity
RNA Binding
Protein Binding
Calmodulin Binding
Identical Protein Binding
Metal Ion Binding
Transcription Regulatory Region Sequence-specific DNA Binding
Nucleic Acid Binding
Chromatin Binding
RNA Binding
Protein Binding
Identical Protein Binding
Biological Process
Regulation Of Transcription, DNA-templated
MRNA Splicing, Via Spliceosome
Activation Of Innate Immune Response
DNA Repair
DNA Recombination
Regulation Of Transcription, DNA-templated
MRNA Processing
Circadian Rhythm
RNA Splicing
Regulation Of Circadian Rhythm
Innate Immune Response
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
Ewing's sarcoma
Myxoid liposarcoma
Clear cell sarcoma of soft tissue
Extraskeletal myxoid chondrosarcoma
GWAS
Breast cancer (
23535729
)
Pancreatic cancer (
25086665
)
Platelet count (
27863252
)
Platelet distribution width (
32888494
)
Interacting Genes
162 interacting genes:
ACTL6A
AGT
ANXA11
ARID1A
ATN1
ATPAF2
ATXN3
BAD
BARD1
BLZF1
BNIP3L
BRME1
BTK
C11orf16
CALM1
CCDC7
CCDC91
CD177
CDK12
CEACAM5
CETP
CFDP1
CHERP
CNST
CPSF6
CPSF7
CREBBP
CUEDC2
CXADR
DFFA
DMRTB1
DNAJB3
DYNLL2
E2F8
ECD
ELAVL3
ELAVL4
ELK1
EPAS1
ERCC5
FAM131C
FASN
FLI1
FUS
FXR2
GNPDA1
GPBP1L1
H2BC15
HBP1
HDAC3
HERPUD1
HLTF
HMGA1
HMGN4
HNRNPUL1
HSPA2
IRF3
ITCH
ITGB5
JUN
KCNMB1
KEL
KHDRBS2
KRR1
KXD1
LILRA3
MAGEA11
MAPK1IP1L
MATK
MDFI
MNS1
MRPS18B
MSC
MTCP1
MTMR9
MVK
MYL6
MYO1F
MYOZ2
NBPF3
NDRG1
NDUFB1
NDUFV1
NINL
NLE1
NONO
NPPB
NSUN4
NTNG2
PCBP1
PDHX
PEF1
PGLS
PLSCR1
POLR2G
POLR3A
POU4F1
POU5F1
PRKCA
PRMT1
PRMT8
PRR13
PRRC2A
PRTFDC1
PRUNE2
PTK2B
RAB37
RAD23A
RALYL
RASL11B
RBPMS
RFX3
RHOXF2
RMND5B
RNF183
RPL31
RPS15A
SALL2
SCMH1
SEC24A
SEC24D
SELENOI
SERP2
SF1
SF3B4
SLC1A1
SLC22A24
SMAD1
SMAD4
SMARCC1
SMARCC2
SNRPC
SSBP2
SSBP3
SUPT4H1
SUV39H2
TAF1
TFG
TMSB4Y
TONSL
TPGS2
TRAF1
TRAF2
TRAF3
TRIM37
TRIM5
TRPV5
TSPAN3
TULP2
USP7
VPS72
WBP4
WDR37
WWP1
WWP2
YWHAG
YY1AP1
ZBTB1
ZDHHC3
ZNF165
ZNF184
ZNF383
115 interacting genes:
APBB1
AR
BHLHE41
C11orf68
CA2
DDX6
DELEC1
ERCC6
ERG
ESR1
EWSR1
FXR2
H3-4
IL7R
IRAK3
LMO4
MAD1L1
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
MYC
MYCN
ORC5
OTUD5
PIN1
PLEKHF2
POLR1H
POLR2A
PPP1CA
PPP1CB
PPP1CC
PRKAA2
PRPF40A
PSPC1
PTBP1
SFPQ
SMARCB1
SMARCC1
SMARCD1
SPI1
SUMO2
SYNPO
TCERG1
UBE2D1
UBE2I
WBP4
Entrez ID
2130
4841
HPRD ID
00592
02098
Ensembl ID
ENSG00000182944
ENSG00000147140
Uniprot IDs
Q01844
A0A0S2Z4Z9
Q15233
PDB IDs
2CPE
3SDE
5IFM
Enriched GO Terms of Interacting Partners
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