ERCC6 and ERCC8

  • Data Source:
  • HPRD (in vitro)

ERCC6

ERCC8

Description ERCC excision repair 6, chromatin remodeling factor ERCC excision repair 8, CSA ubiquitin ligase complex subunit
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Pulse pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Brain morphology (MOSTest) ( 32665545)
  • Cortical surface area (MOSTest) ( 32665545)
  • Subcortical volume (MOSTest) ( 32665545)
Interacting Genes 118 interacting genes: ACTR2 ACTR3 ARPC1A ATP5F1C ATP5PO BRCA1 CAVIN1 CCT5 CCT6A CHEK2 CLIC4 COPE CORO1C CSNK2A2 CSNK2B CTSB CUL5 DARS1 ECHS1 EIF3C EIF3D EIF3F EIF3I EIF3L EIF4A3 ELOA ERCC5 ERCC8 FBLN2 FNDC3B FOSL1 FXR1 FYTTD1 GATAD2B GRPEL1 GTF2E2 GTF2I H2BC3 H3C1 H4C1 HDAC1 HDAC2 HNRNPUL2 HSPA5 HSPA9 HTATSF1 IARS2 IDH3G IWS1 LEO1 MBD3 MORC3 MRPL11 MRPL13 MRPL20 MRPL21 MRPL3 MRPL38 MRPL4 MRPL47 MRPL50 MRPL58 MRPS18B MRPS22 MRPS25 MRPS26 MTA1 MTA2 MTA3 NAP1L1 NONO NPLOC4 PAF1 PARP1 PCNA PFN2 PML POLR2A POLR2H PPIA PSMC5 RBBP4 RBBP7 RCC1 RHOG RNF11 RPL10 RPL13 RPL30 RPL39 RPL5 RPS15 RPS15A RPS24 RPS29 RPS6 SAE1 SDHA SENP2 SF3B3 SLC39A7 SNRPD1 SUMO1 SUMO2 SUPT6H TACO1 TP53 TPR UBA2 UBC UBE2I UQCRC1 UQCRQ USP7 XAB2 XPA XRCC5 ZBTB38 11 interacting genes: CAMK2D CBR1 CSNK2B CUL4A DDB1 ERCC6 GTF2H2 RBX1 TOP1 UQCRQ XAB2
Entrez ID 2074 1161
HPRD ID 00596 07523
Ensembl ID ENSG00000225830 ENSG00000049167
Uniprot IDs A8K4Q3 P0DP91 Q03468 Q59FF6 A0A0S2Z3L1 B3KPW7 B4DGZ9 Q13216
PDB IDs 4CVO 6A6I 4A11 6FCV
Enriched GO Terms of Interacting Partners?
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